{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:10:41Z","timestamp":1787019041178,"version":"build-2736575974"},"reference-count":24,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T00:00:00Z","timestamp":1738454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Objective<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>To study postoperative pain control differences between liposomal bupivacaine (LB) and immediate-release bupivacaine (IRB) as measured by the use of narcotics after iliac crest graft harvesting for alveolar bone grafting (ABG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Design<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>A retrospective review was completed at a single-site pediatric stand-alone hospital of patients undergoing ABG with iliac crest bone grafting (ICBG) between May 1, 2020, through May 31, 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients, Participants<\/jats:title>\n                    <jats:p>Patients who underwent ABG with ICBG were split into three cohorts: LB monotherapy, IRB monotherapy, or LB with IRB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>All ABG and ICBG procedures were completed by a single surgeon who is a member of our dedicated cleft lip and palate team.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>The primary outcome was the difference in oral morphine equivalent (OME) requirements from the immediate postoperative time period to the time of discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Results<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>\n                      Patients treated with LB monotherapy required significantly less OME during their inpatient stay, with an average of 0.21\u2005mg\/kg\u2009\u00b1\u20090.15\u2005mg\/kg in the LB group, 0.67\u2005mg\/kg\u2009\u00b1\u20090.37\u2005mg\/kg in the IRB group, and 0.28\u2005mg\/kg\u2009\u00b1\u20090.07\u2005mg\/kg in the LB with IRB group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .001). There was no significant difference in the total number of analgesic medication doses administered throughout the hospitalization among the three groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Conclusions<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Utilization of LB intraoperatively may decrease the need for postoperative opioid treatment for postoperative pain control when harvesting ICB for ABG in the cleft lip and palate population compared to alternative local anesthetics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656251317600","type":"journal-article","created":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T23:43:11Z","timestamp":1738539791000},"page":"967-972","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Liposomal Bupivacaine for Additional Analgesia at Iliac Crest Donor Site in Alveolar Bone Graft Surgery: A Retrospective Pilot Study"],"prefix":"10.1177","volume":"63","author":[{"given":"Daniel E.","family":"Sampson","sequence":"first","affiliation":[{"name":"Children's Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Tibesar","sequence":"additional","affiliation":[{"name":"Children's Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Tibesar","sequence":"additional","affiliation":[{"name":"Children's Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Finch","sequence":"additional","affiliation":[{"name":"Research Institute, Children's Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"Rabusch","sequence":"additional","affiliation":[{"name":"Children's Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6181-4756","authenticated-orcid":false,"given":"Michael","family":"Raschka","sequence":"additional","affiliation":[{"name":"Children's Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,2]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002778"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/10556656211007692"},{"key":"e_1_3_3_4_2","doi-asserted-by":"crossref","unstructured":"Skaggs DL Samuelson MA Hale JM Kay RM Tolo VT. Complications of posterior iliac crest bone grafting in spine surgery in children. Spine (Phila Pa 1976). 2000;25(18):2400\u20132402. doi:https:\/\/doi.org\/10.1097\/00007632-200009150-00021.","DOI":"10.1097\/00007632-200009150-00021"},{"key":"e_1_3_3_5_2","unstructured":"The Opioid Epidemic in the United States. State Health Access Data Assistance Center (Shadac). Accessed July 28 2024. https:\/\/www.shadac.org\/opioid-epidemic-united-states"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-2439"},{"key":"e_1_3_3_7_2","unstructured":"Exparel. Package insert. Pacira Pharmaceuticals Inc. updated November 30 2023."},{"key":"e_1_3_3_8_2","unstructured":"Exparel. Proprietary multivesicular liposome (pMVL) technology. Accessed July 28 2023. https:\/\/www.exparelpro.com\/about-exparel\/pmvl-technology"},{"key":"e_1_3_3_9_2","volume-title":"Clinical Anesthesia","author":"Barash PG","year":"2009","unstructured":"Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Christine Stock M (eds). Clinical Anesthesia. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2009.","edition":"6"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000006310"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000009966"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13561"},{"key":"e_1_3_3_13_2","first-page":"8092204","article-title":"Use of liposomal bupivacaine in pediatric peripheral nerve blocks after traumatic amputation","volume":"2021","author":"Halenda GM","year":"2021","unstructured":"Halenda GM, Voulgarelis S. Use of liposomal bupivacaine in pediatric peripheral nerve blocks after traumatic amputation. Case Rep Anesthesiol. 2021;2021:8092204. doi:https:\/\/doi.org\/10.1155\/2021\/8092204","journal-title":"Case Rep Anesthesiol"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000004312"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2019.09.026"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2021.04.003"},{"key":"e_1_3_3_17_2","first-page":"5521136","article-title":"A novel use of liposomal bupivacaine in erector spinae plane block for pediatric congenital cardiac surgery","volume":"2021","author":"Voulgarelis S","year":"2021","unstructured":"Voulgarelis S, Halenda GM, Tanem JM. A novel use of liposomal bupivacaine in erector spinae plane block for pediatric congenital cardiac surgery. Case Rep Anesthesiol. 2021;2021:5521136. doi:https:\/\/doi.org\/10.1155\/2021\/5521136.","journal-title":"Case Rep Anesthesiol"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.36469\/jheor.2021.21967"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2021.110503"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.3171\/2020.6.PEDS20370"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13482"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2023.01.056"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2021.08.025"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2021.02.014"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2014.01.2733"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10556656251317600","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10556656251317600","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10556656251317600","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:22:27Z","timestamp":1777393347000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10556656251317600"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,2]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1177\/10556656251317600"],"URL":"https:\/\/doi.org\/10.1177\/10556656251317600","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,2]]}}}