{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T22:33:48Z","timestamp":1787697228673,"version":"build-2784847793"},"reference-count":29,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,5]]},"abstract":"\n \n Objective<\/jats:italic>\n <\/jats:title>\n To compare outcomes, complications, and costs between endoscopic and open surgical approaches in the management of craniosynostosis using a large national database.<\/jats:p>\n <\/jats:sec>\n \n \n Design<\/jats:italic>\n <\/jats:title>\n Retrospective cohort study.<\/jats:p>\n <\/jats:sec>\n \n \n Setting<\/jats:italic>\n <\/jats:title>\n National Inpatient Sample database, including inpatient hospital discharge data from 2018 to 2021 across 48 states and Washington, D.C.<\/jats:p>\n <\/jats:sec>\n \n \n Patients<\/jats:italic>\n <\/jats:title>\n The present study included 1099 patients admitted with a primary diagnosis of craniosynostosis. Among them, 183 (16.6%) underwent endoscopic surgery and 916 (83.3%) underwent open surgery.<\/jats:p>\n <\/jats:sec>\n \n \n Interventions<\/jats:italic>\n <\/jats:title>\n Surgical management of craniosynostosis, classified as either an endoscopic or open approach.<\/jats:p>\n <\/jats:sec>\n \n \n Main Outcome Measure(s)<\/jats:italic>\n <\/jats:title>\n Length of hospital stay, total procedure costs, and rates of inpatient complications, including surgical and medical complications.<\/jats:p>\n <\/jats:sec>\n \n \n Results<\/jats:italic>\n <\/jats:title>\n \n Endoscopic surgery was associated with a significantly shorter length of stay (mean 1.6 days vs 3.7 days,\n P<\/jats:italic>\n \u2009<\u2009.001) and lower total costs ($ 66\u2005815.90 vs $ 146\u2005271.21,\n P<\/jats:italic>\n \u2009<\u2009.001) compared to open procedures. It demonstrated lower rates of surgical complications (0.5% vs 7.9%,\n P<\/jats:italic>\n \u2009<\u2009.001) and neurologic complications, primarily dural tears (0.5% vs 7.0%,\n P<\/jats:italic>\n \u2009<\u2009.001). There were no differences in inpatient mortality between groups.\n <\/jats:p>\n <\/jats:sec>\n \n \n Conclusions<\/jats:italic>\n <\/jats:title>\n Endoscopic approaches to craniosynostosis offer advantages over open techniques, including reduced length of stay, costs, and complications. The present findings support the increasing adoption of endoscopic methods for craniosynostosis management. Future studies should assess the long-term impact on head shape durability and neurodevelopmental outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/10556656251320746","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:22:39Z","timestamp":1740108159000},"page":"1032-1042","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Complication Rates and Cost of Endoscopic and Open Surgical Approaches to Management of Craniosynostosis: A Large, National, Inpatient Cohort Evaluation"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0337-8020","authenticated-orcid":false,"given":"Daniel Y.","family":"Kwon","sequence":"first","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dillan F.","family":"Villavisanis","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Choe","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nargiz","family":"Seyidova","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olachi","family":"Oleru","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Shamamian","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Wang","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Sarosi","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Taub","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"issue":"3","key":"e_1_3_2_2_2","first-page":"247","article-title":"Endoscopic craniosynostosis repair","volume":"3","author":"Proctor MR","year":"2014","unstructured":"Proctor MR. Endoscopic craniosynostosis repair. Transl Pediatr. 2014;3(3):247-258.","journal-title":"Transl Pediatr"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3171\/2015.7.PEDS15187"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000002454"},{"key":"e_1_3_2_5_2","unstructured":"HCUP-US NIS overview. Accessed November 4 2024. https:\/\/hcup-us.ahrq.gov\/nisoverview.jsp"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/10556656221085478"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000250846.12958.05"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3171\/2013.12.PEDS13320"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3182646ab8"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2024.108296"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-018-3852-4"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.03.048"},{"issue":"5","key":"e_1_3_2_13_2","article-title":"A statistical skull geometry model for children 0-3 years old","volume":"10","author":"Li Z","year":"2015","unstructured":"Li Z, Park BK, Liu W, Zhang J, Reed MP, Rupp JD, Hoff CN, Hu J. A statistical skull geometry model for children 0-3 years old. PLoS One. 2015;10(5):e0127322.","journal-title":"PLoS One"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3171\/2021.12.PEDS21541"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-022-05752-9"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31828696a5"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000007178"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e318240f965"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyx209"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000001651"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2021.08.165"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.3171\/2019.11.PEDS19515"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2019.09.037"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200108000-00013"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000003072"},{"issue":"2","key":"e_1_3_2_26_2","first-page":"105","article-title":"Endoscopic versus open cranial reconstruction surgery for anterior craniosynostosis: experience from South-East Asia","volume":"1","author":"Mendonca DA","year":"2020","unstructured":"Mendonca DA, Gopal S, Gujjalanavar R, Deraje V, Sunil HR, Ramamurthy V. Endoscopic versus open cranial reconstruction surgery for anterior craniosynostosis: experience from South-East Asia. FACE (Thousand Oaks). 2020;1(2):105-113.","journal-title":"FACE (Thousand Oaks)"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-008-0691-8"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199812000-00002"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198904000-00021"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000182131.44670.f7"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10556656251320746","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10556656251320746","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10556656251320746","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:22:28Z","timestamp":1777393348000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10556656251320746"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,21]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1177\/10556656251320746"],"URL":"https:\/\/doi.org\/10.1177\/10556656251320746","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,21]]}}}