{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:32:47Z","timestamp":1777588367198,"version":"3.51.4"},"reference-count":84,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To synthesize research exploring the impact of surgery on quality of life (QoL) in families of children with a cleft lip and\/or palate (CL\/P).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Medline, PsycINFO, CINAHL, and ProQuest databases were systematically searched (from database inception to July 2024) to identify studies exploring QoL in families following surgery for a child with CL\/P. Studies were quality appraised using Quality Assessment for Diverse Studies criteria, and a narrative synthesis was undertaken.<\/jats:p>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Main Outcome Measure:<\/jats:italic>\n                      Quality of life was explored but specific measures varied across studies.\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Interventions:<\/jats:italic>\n                      Type of surgery being investigated varied across the reviewed studies. This systematic review focussed on both functional and aesthetic surgeries throughout childhood.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 157 identified studies, 9 were eligible for inclusion (1 mixed-methods, 1 observational, 1 qualitative, 2 cross-sectional, 4 quasi-experimental). Analysis indicated that QoL was positively impacted by surgery through reduced financial burden, increased sense of mastery\/coping, and reduced social impact. However, for some families, new demands (eg, medical\/dental appliances, food restrictions), intolerance of uncertainty, and adjustment to changes to their child's appearance were identified following surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is limited qualitative and quantitative research exploring the impact of a child's cleft surgery on family QoL. The quality of studies included in the review was variable. Supporting families accessing cleft services, especially where QoL and mental health are negatively impacted, is important. Due to the variability within and between the studies, and lack of detail relating to rationale and processes taken, the conclusions from this review are tentative. Further research is needed that addresses methodological and conceptual limitations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656251321902","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T11:32:11Z","timestamp":1742211131000},"page":"1018-1031","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Surgery on Quality of Life in Families of Children With a Cleft Lip and\/or Palate: A Systematic Review"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6755-5022","authenticated-orcid":false,"given":"Jessica","family":"Ferguson","sequence":"first","affiliation":[{"name":"University of Lincoln"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"De Boos","sequence":"additional","affiliation":[{"name":"University of Nottingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0205-6596","authenticated-orcid":false,"given":"Laura","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Nottingham University Hospitals NHS Trust"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,3,17]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jormas.2021.05.008"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.15761\/OHNS.1000246"},{"issue":"03","key":"e_1_3_3_4_2","first-page":"1","article-title":"Cleft lip and palate: etiology, epidemiology, preventive and intervention strategies","volume":"04","author":"Allam E","year":"2014","unstructured":"Allam E, Windsor L J, Stone C. Cleft lip and palate: etiology, epidemiology, preventive and intervention strategies. Anat Physiol. 2014;04(03):1-6. doi:https:\/\/doi.org\/10.4172\/2161-0940.1000150","journal-title":"Anat Physiol"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1597\/07-048.1"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/028443102753478327"},{"key":"e_1_3_3_7_2","unstructured":"NHS England. Specialised Services Quality Dashboards \u2013 Women and children metric definitions for 2022\/23. April 2022. Accessed July 21 2023. https:\/\/www.england.nhs.uk\/publication\/specialised-services-quality-dashboards-women-and-children-metric-definitions-for-2022-23\/."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0965539505001452"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13005-016-0132-y"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-015-3374-0"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0080-623420160000200006"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1597\/05-080"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpolmod.2013.06.002"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13690-020-00402-5"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-009-0138-x"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-79722012000300007"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedhc.2017.08.003"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/JPS.0000000000000343"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2920"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2015.04.024"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1597\/10-018"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10826-020-01784-4"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.23.2.207"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10826-023-02556-6"},{"key":"e_1_3_3_25_2","unstructured":"World Health Organization. Programme on mental health: WHOQOL user manual 2012 revision. March 2012. Accessed July 28 2023. https:\/\/iris.who.int\/handle\/10665\/77932."},{"key":"e_1_3_3_26_2","volume-title":"StatPearls","author":"Teoli D","year":"2023","unstructured":"Teoli D, Bhardwaj A. Quality of life. In: StatPearls. StatPearls Publishing; 2023. Accessed July 31, 2023. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK536962\/"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31822b6a67"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.109598"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.06.037"},{"issue":"1","key":"e_1_3_3_30_2","first-page":"34","article-title":"Quality-of-life evaluation of healthy siblings of children with chronic illness","volume":"37","author":"Dinleyici M","year":"2019","unstructured":"Dinleyici M, Carman KB, \u00d6zdemir C, Harmanci K, Eren M, Kirel B, Simsek E, Yarar C, Duyan Camurdan A, Sahin Dagli F. Quality-of-life evaluation of healthy siblings of children with chronic illness. Balk Med J. 2019;37(1):34-42. doi:https:\/\/doi.org\/10.4274\/balkanmedj.galenos.2019.2019.7.142","journal-title":"Balk Med J"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1177\/2374373520948650"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-020-09639-9"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2019.04.005"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp20X713897"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.121349"},{"key":"e_1_3_3_36_2","volume-title":"Stress, Appraisal, and Coping","author":"Lazarus RS","year":"1984","unstructured":"Lazarus RS, Folkman S. Stress, Appraisal, and Coping. Springer Publishing Company, Incorporated; 1984. Accessed November 3, 2023. http:\/\/ebookcentral.proquest.com\/lib\/nottingham\/detail.action?docID=423337"},{"key":"e_1_3_3_37_2","first-page":"199","volume-title":"Handbook of Stress, Coping, and Health: Implications for Nursing Research, Theory, and Practice. 2nd ed","author":"Lazarus RS","year":"2012","unstructured":"Lazarus RS. Chapter 9: evolution of a model of stress, coping, and discrete emotions. In: Handbook of Stress, Coping, and Health: Implications for Nursing Research, Theory, and Practice. 2nd ed. Sage Publications, Inc.; 2012:199-225. Accessed November 3, 2023. https:\/\/archive.org\/details\/handbookofstress0002unse"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2011.11.004"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000007071"},{"issue":"7","key":"e_1_3_3_40_2","first-page":"91","article-title":"A systematic review of the quality of life of carers of children with cleft lip and\/or palate","volume":"2","author":"Vella SL","year":"2012","unstructured":"Vella SL, Pai N. A systematic review of the quality of life of carers of children with cleft lip and\/or palate. Int J Health Sci Res. 2012;2(7):91-96.","journal-title":"Int J Health Sci Res"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-021-01626-4"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.7326\/ACPJC-1995-123-3-A12"},{"key":"e_1_3_3_43_2","volume-title":"Systematic Reviews: CRD\u2019s Guidance for Undertaking Reviews in Health Care","author":"Centre for Reviews and Dissemination","year":"2008","unstructured":"Centre for Reviews and Dissemination. Systematic Reviews: CRD\u2019s Guidance for Undertaking Reviews in Health Care. York Publishing Services Ltd.; 2008. Accessed August 17, 2023. https:\/\/www.york.ac.uk\/media\/crd\/Systematic_Reviews.pdf"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-021-06122-y"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2753.2011.01662.x"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0280014"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2022.02.017"},{"key":"e_1_3_3_48_2","volume-title":"Guidance on the Conduct of Narrative Synthesis in Systematic Reviews: A Product From the ESRC Methods Programme","author":"Popay J","year":"2006","unstructured":"Popay J, Roberts H, Sowden A, Petticrew M, Arai L, Rodgers M, Britten N, Roen K, Duffy S. Guidance on the Conduct of Narrative Synthesis in Systematic Reviews: A Product From the ESRC Methods Programme. Lancaster University; 2006."},{"issue":"2","key":"e_1_3_3_49_2","first-page":"1","article-title":"PRISMA2020: an R package and shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and open synthesis","volume":"18","author":"Haddaway NR","year":"2022","unstructured":"Haddaway NR, Page MJ, Pritchard CC, McGuinness LA. PRISMA2020: an R package and shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and open synthesis. Campbell Syst Rev. 2022;18(2):1-12. doi:https:\/\/doi.org\/10.1002\/cl2.1230","journal-title":"Campbell Syst Rev"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1177\/10556656231181581"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.5125\/jkaoms.2017.43.4.247"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181be8892"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1177\/1055665621993282"},{"issue":"6","key":"e_1_3_3_54_2","first-page":"370","article-title":"Impact of cleft lip and\/or palate in children on family quality of life before and after reconstructive surgery","volume":"118","author":"Macho P","year":"2017","unstructured":"Macho P, Bohac M, Fedeles J, Fekiacova D, Fedeles J. Impact of cleft lip and\/or palate in children on family quality of life before and after reconstructive surgery. Bratisl Lek Listy. 2017;118(6):370-373. doi:https:\/\/doi.org\/10.4149\/BLL_2017_070","journal-title":"Bratisl Lek Listy"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.15386\/mpr-2472"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1037\/hea0000262"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181ec6872"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jormas.2019.11.002"},{"key":"e_1_3_3_59_2","volume-title":"Second Language Research: Methodology and Design","author":"Mackey A","year":"2005","unstructured":"Mackey A, Gass SM. Second Language Research: Methodology and Design. Lawrence Erlbaum Associates, Inc.; 2005."},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1037\/a0012765"},{"key":"e_1_3_3_61_2","volume-title":"Discovering Statistics Using R","author":"Field A","year":"2012","unstructured":"Field A, Miles J, Field Z. Discovering Statistics Using R. Sage; 2012."},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.26458\/1746"},{"issue":"2","key":"e_1_3_3_63_2","first-page":"60","article-title":"Cross cultural adaptation and validation of the early childhood health impact scale (ECOHIS) in Peruvian preschoolers","volume":"26","author":"L\u00f3pez Ramos RP","year":"2013","unstructured":"L\u00f3pez Ramos RP, Garc\u00eda Rupaya CR, Villena-Sarmiento R, Bordoni NE. Cross cultural adaptation and validation of the early childhood health impact scale (ECOHIS) in Peruvian preschoolers. Acta Odontol Latinoam AOL. 2013;26(2):60-67.","journal-title":"Acta Odontol Latinoam AOL"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-2-55"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-198004000-00010"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.2013.006015"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(96)00339-5"},{"issue":"2","key":"e_1_3_3_68_2","article-title":"Quantitative and qualitative analysis of the quality of life of individuals with eating disorders","volume":"17","author":"Pollack LO","year":"2015","unstructured":"Pollack LO, McCune AM, Mandal K, Lundgren JD. Quantitative and qualitative analysis of the quality of life of individuals with eating disorders. Prim Care Companion CNS Disord. 2015;17(2). doi:https:\/\/doi.org\/10.4088\/PCC.14m01667","journal-title":"Prim Care Companion CNS Disord"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1597\/08-075.1"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2016.1140902"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1080\/00207411.1994.11449281"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1597\/09-046"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.02.012"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.5897"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.2017.027136"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2019.11.014"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1597\/03-142.1"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10608-018-9964-z"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-022-02254-1"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.5177\/ntvt2010.04.08153"},{"issue":"2","key":"e_1_3_3_81_2","first-page":"169","article-title":"Analysis of quality of life of 115 parents with cleft lip and\/or palate children","volume":"33","author":"Zhang Y","year":"2015","unstructured":"Zhang Y, Gong C, Wu H, Chen Y, Zhang X, Liang Y, Pin H, Bing S. Analysis of quality of life of 115 parents with cleft lip and\/or palate children. Hua Xi Kou Qiang Yi Xue Za Zhi. 2015;33(2):169-173.","journal-title":"Hua Xi Kou Qiang Yi Xue Za Zhi"},{"issue":"3","key":"e_1_3_3_82_2","first-page":"279","article-title":"Study on life quality and influence factors in cleft lip and palate parents","volume":"31","author":"Kun Z","year":"2013","unstructured":"Kun Z, Xiong Y, Yan-Hua X, Zhongwei Z, Jian M, Jinfang Z, Yirui W, Yongqing H. Study on life quality and influence factors in cleft lip and palate parents. Hua Xi Kou Qiang Yi Xue Za Zhi. 2013;31(3):279-282.","journal-title":"Hua Xi Kou Qiang Yi Xue Za Zhi"},{"key":"e_1_3_3_83_2","unstructured":"Service specifications. NHS England. 2013. Accessed September 5 2024. https:\/\/www.england.nhs.uk\/wp-content\/uploads\/2018\/08\/Cleft-lip-and-or-palate-services-including-non-cleft-velopharyngeal-dysfunction-all-ages.pdf."},{"issue":"11","key":"e_1_3_3_84_2","article-title":"How to conduct a systematic review: a narrative literature review","volume":"8","author":"Jahan N","year":"2016","unstructured":"Jahan N, Naveed S, Zeshan M, Tahir MA. How to conduct a systematic review: a narrative literature review. Cureus. 2016;8(11):e864. doi:https:\/\/doi.org\/10.7759\/cureus.864","journal-title":"Cureus"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0000000000000765"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10556656251321902","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10556656251321902","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10556656251321902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:22:29Z","timestamp":1777393349000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10556656251321902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,17]]},"references-count":84,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1177\/10556656251321902"],"URL":"https:\/\/doi.org\/10.1177\/10556656251321902","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,17]]}}}