{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T03:48:37Z","timestamp":1783396117100,"version":"3.54.6"},"reference-count":20,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Assessment of simultaneous 3-dimensional facial and maxillary archform changes after primary lip repair in cUCLP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective longitudinal case series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings<\/jats:title>\n                    <jats:p>King's College London, United Kingdom.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Consecutive facial plaster cast sets of 18 infants with cUCLP, pre lip (3 months), and pre palate repair (6 months).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Single Consultant Cleft Plastic Surgeon in single cleft area operated on all cases and created all casts once anesthetized. One operator scanned all casts, exporting .stl files for analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>\n                      Twenty-six facial and maxillary arch landmarks were defined. From these, 11 variables describing linear and volumetric changes were calculated. Landmark identification precision was assessed through a repeatability study. Color maps for visualization of changes after lip repair were created by superimposition. Parametric 1- and 2- sample\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      tests were used to compare changes between lip and palate repairs. The study had sufficient power (0.80). Clinically significant changes were defined \u22652\u2005mm for nose and \u22654\u2005mm for cleft widths, and \u22655\u2005mm3 for nose and \u22652\u2005mm\n                      <jats:sup>3<\/jats:sup>\n                      for maxillary archform volumes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Good precision of landmark identification was confirmed. The main study showed a statistically and clinically significant decrease in overall nasal width (3.24 mm, 95%CI [1.76, 4.71],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =\u2009.04) and decrease in average cleft width volume (4.62 mm\n                      <jats:sup>3<\/jats:sup>\n                      , 95% CI [2.58, 6.66],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;\u2009.01) after lip repair. Color maps showed concordance with numerical findings.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>After lip repair, there was simultaneous nose width reduction, better nasal symmetry, changes in overall palatal alveolar ridges volume, and decrease in volume of alveolar cleft and anterior ridge of palate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656251323692","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T11:32:11Z","timestamp":1742211131000},"page":"981-988","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Simultaneous 3-Dimensional Facial and Maxillary Archform Changes After Primary Lip Repair in Complete Unilateral Cleft Lip and Palate"],"prefix":"10.1177","volume":"63","author":[{"given":"Abeera","family":"Imran","sequence":"first","affiliation":[{"name":"Luton and Dunstable University Hospital NHS Foundation Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6859-6918","authenticated-orcid":false,"given":"Nazan","family":"Adali","sequence":"additional","affiliation":[{"name":"Luton and Dunstable University Hospital NHS Foundation Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Consultant Cleft Plastic Surgeon, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Bister","sequence":"additional","affiliation":[{"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7122-7980","authenticated-orcid":false,"given":"Trevor","family":"Coward","sequence":"additional","affiliation":[{"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,3,17]]},"reference":[{"issue":"4","key":"e_1_3_2_2_2","first-page":"605","article-title":"Accuracy of facial plaster casts","volume":"76","author":"Holberg C","year":"2006","unstructured":"Holberg C, Schwenzer K, Mahaini L, Rudzki-Janson I. Accuracy of facial plaster casts. Angle Orthod. 2006;76(4):605-611. doi:https:\/\/doi.org\/10.1043\/00033219(2006)076[0605:AOFPC]2.0.CO;2","journal-title":"Angle Orthod"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1348-8643(13)00005-0"},{"issue":"11","key":"e_1_3_2_4_2","first-page":"1537","article-title":"Facial aesthetic outcome analysis in unilateral cleft lip and palate surgery using web-based extended panel assessment","volume":"69","author":"Bella H","year":"2016","unstructured":"Bella H, Kornmann NS, Hardwicke JT, Wallis KL, Wearn C, Su TL, Richard BM. Facial aesthetic outcome analysis in unilateral cleft lip and palate surgery using web-based extended panel assessment. 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