{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T05:09:34Z","timestamp":1793768974663,"version":"4.6.1"},"reference-count":50,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the impact of nasoalveolar molding (NAM) treatment after cheiloplasty surgery on the results of nasal symmetry in individuals with cleft lip and\/or cleft palate (CL\/P).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Electronic searches were performed in 6 databases in October 2023. Studies comparing individuals with CL\/P undergoing treatment with NAM\u2009+\u2009cheiloplasty and individuals undergoing cheiloplasty alone were considered. Each selected study was allocated in a table and data were extracted by 2 authors. The risk of bias and meta-analyze were conducted. In total, 416 articles were retrieved and 9 studies were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients, Participants<\/jats:title>\n                    <jats:p>Individuals with CL\/P who underwent cheiloplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>NAM treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure(s)<\/jats:title>\n                    <jats:p>Nasal symmetry, clef width, or any.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the group NAM+ cheiloplasty, there was an increase in nostril height (NH), columellar width, and length (CL) in the short and long term (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05). Nostril width (NW) and bialar width (BW) decreased in the short term and increased in the long term in individuals undergoing NAM+ cheiloplasty (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05). Six studies exhibited a moderate risk of bias; 3 exhibited a serious risk of bias. The strength of the evidence was very low.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Treatment with NAM+ cheiloplasty positively impacted nasal symmetry with increased NH, NW, and CL in the short and long term. NAM treatment improved NW and BW only in the short term.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656251346368","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T02:49:14Z","timestamp":1749523754000},"page":"1688-1700","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Nasal Symmetry Outcomes After Nasoalveolar Molding (NAM) Plus Cheiloplasty Treatment in Babies With Cleft Lip\/Palate: Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3437-6765","authenticated-orcid":false,"given":"T\u00e2nia Mara de","family":"Souza","sequence":"first","affiliation":[{"name":"Federal University of Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lia","family":"de Abreu Refaxo","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7643-6589","authenticated-orcid":false,"given":"Soraia","family":"Macari","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2258-8071","authenticated-orcid":false,"given":"Lucas Guimar\u00e3es","family":"Abreu","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,9]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1999_036_0486_pnmiiw_2.3.co_2"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/10556656221136325"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-023-02039-7"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2018.2.21020"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e318200d874"},{"issue":"5","key":"e_1_3_2_7_2","first-page":"293","article-title":"Nasoalveolar molding in complete cleft lip nasal deformity patients","volume":"113","author":"Fedeles J","year":"2012","unstructured":"Fedeles JJr, Ziak P, Fedeles J. 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