{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T16:28:12Z","timestamp":1787588892830,"version":"build-2736575974"},"reference-count":51,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study was to systematically analyze the cleft lip and\/or palate (CL\/P) literature published between 2000 and 2025 to identify dominant research themes, temporal trends, and potential gaps by applying a natural language processing-based topic modeling approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>We analyzed articles retrieved from the Scopus database and identified thematic clusters using the BERTopic algorithm, which integrates BERT embeddings, Uniform Manifold Approximation and Projection dimensionality reduction, and Hierarchical Density-Based Spatial Clustering of Applications with Noise clustering.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>This study exclusively examined articles related to CL\/P.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Participants<\/jats:title>\n                    <jats:p>This study involved no patients or participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Not applicable as this is a BERTopic-based analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Outcomes included identifying dominant research topics, trend analysis, distribution across countries and journals, and classifying topics as \u201chot\u201d or \u201ccold\u201d based on temporal trends.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 29 thematic clusters. The most common topics included \u201cVelopharyngeal Dysfunction and Fistula Repair,\u201d \u201cNonsyndromic Cleft Lip and Palate and Genetic Associations,\u201d and \u201cUnilateral Cleft Lip and Palate and Maxillofacial Asymmetry.\u201d \u201cQuality of Life and Psychosocial Impact in Children,\u201d \u201cSurgical Repair Approaches,\u201d and \u201cPresurgical Nasoalveolar Molding Techniques\u201d emerged as \u201chot topics.\u201d The United States led in publication volume, while certain topics dominated in specific countries. The\n                      <jats:italic toggle=\"yes\">Cleft Palate-Craniofacial Journal<\/jats:italic>\n                      published the most articles.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study provides a comprehensive thematic map of CL\/P research, highlighting strengths and underexplored areas. BERTopic offers an efficient, scalable method for analyzing large-scale scientific literature and identifying future research priorities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656251384747","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:34:48Z","timestamp":1760027688000},"page":"2553-2564","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Analysis of Research Trends in Cleft Lip and Palate: A Topic Modeling Study"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5298-7949","authenticated-orcid":false,"given":"Ru\u015fen","family":"Erdem","sequence":"first","affiliation":[{"name":"Kafkas University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8674-5276","authenticated-orcid":false,"given":"Burkay","family":"Moro\u011flu","sequence":"additional","affiliation":[{"name":"Atat\u00fcrk University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1753-3236","authenticated-orcid":false,"given":"Nurbanu","family":"Moro\u011flu","sequence":"additional","affiliation":[{"name":"Atat\u00fcrk University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0556-2830","authenticated-orcid":false,"given":"Yavuz Selim","family":"Gen\u00e7","sequence":"additional","affiliation":[{"name":"Samsun Oral and Dental Health Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6804-1276","authenticated-orcid":false,"given":"Ahmet","family":"Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[{"name":"Bulent Ecevit University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,9]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_472_20"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddh052"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/154405910808700202"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2933"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60695-4"},{"key":"e_1_3_2_7_2","volume-title":"Global Strategies to Reduce the Health-Care Burden of Craniofacial Anomalies","author":"World Health Organization","year":"2002","unstructured":"World Health Organization. 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