{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:14:35Z","timestamp":1783426475109,"version":"3.54.6"},"reference-count":51,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Objective<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>To determine the effect of early hard palate closure by means of a Vomer flap (VF) on the nutritional status of children with cleft lip and palate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Design<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Multicenter retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Setting<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Three referral centers for oral clefts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Patients, Participants<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Nonsyndromic children with UCLP or BCLP.<\/jats:p>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Interventions:<\/jats:italic>\n                      Early hard palate closure with a VF at cheiloplasty around 3 months versus isolated cheiloplasty, both followed by palatoplasty around 9 to 10 months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Main Outcome Measure(s)<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Anthropometric measures (weight and height) and related weight-for-age and height-for-age Z-scores at the time of cheiloplasty and palatoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Results<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>\n                      Between 2012 and 2024, 122 children with UCLP or BCLP underwent cleft repair surgery. Median age at cheiloplasty was 111 (99-126) days and 304 (284-342) at palatoplasty. In 60% of them (n\u2009=\u200973), a VF was performed simultaneously with cheiloplasty. Weight increase between cheiloplasty and palatoplasty was slightly more for the VF group compared to the control group by 0.24 kg (SE\u2009=\u20090.15,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.13). No height difference was measured between the groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.80). Z-score variation between cheiloplasty and palatoplasty was significantly different for all study groups, indicating a strong normalization of the growth curve after cheiloplasty (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Conclusions<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Early hard palate closure using a VF may favor growth in children with cleft lip and palate. The deviation from the normative growth curve of infants decreases significantly between cheiloplasty and palatoplasty, regardless of whether a VF was performed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656251385010","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:35:24Z","timestamp":1760027724000},"page":"2534-2543","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Vomer Flap on Nutritional Status in Infants With Cleft Lip and Palate: A Multicenter Retrospective Cohort Study"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9529-0147","authenticated-orcid":false,"given":"Sofia","family":"Bachini","sequence":"first","affiliation":[{"name":"Frisius Medical Center Leeuwarden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Delnoij","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0885-7722","authenticated-orcid":false,"given":"Edith","family":"Visser","sequence":"additional","affiliation":[{"name":"Frisius Medical Center Leeuwarden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Moues-Vink","sequence":"additional","affiliation":[{"name":"Frisius Medical Center Leeuwarden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3587-7489","authenticated-orcid":false,"given":"Corstiaan C.","family":"Breugem","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,9]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0891-5245(00)70039-3"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-6343.2007.00398.x"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2933"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(09)60695-4"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jormas.2021.05.008"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2013.00053"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_472_20"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/10556656221149144"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1597\/02-148.1"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2021.101280"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.76.1.70a"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1597\/05-172"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/bf03262817"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2022.11.030"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40795-025-01031-3"},{"key":"e_1_3_4_17_2","first-page":"400","article-title":"Height-weight growth of cleft children, birth to six years","volume":"12","author":"Ranalli DN","year":"1975","unstructured":"Ranalli DN, Mazaheri M. 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