{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:35:57Z","timestamp":1792787757585,"version":"4.5.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Dr Allan G Brodie Chair Endowment","id":[{"id":"https:\/\/ror.org\/0229evh14","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Dr. Robert and Donna Litowitz Term Gift"},{"DOI":"10.13039\/100005648","name":"American Association of Orthodontists Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005648","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the association between the occurrence of cleft lip and\/or palate (CLP) in newborns (compared to newborns without CLP) and in-hospital outcomes such as mortality, length of stay (LOS), and hospital charges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>National.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>The National Inpatient Sample database for the years 2020-2022 was used in the present study. All newborns were included in the study. They were grouped into newborns born with CLP and newborns without CLP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>None.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome variable<\/jats:title>\n                    <jats:p>In-hospital mortality, LOS, and hospital charges. Multivariable regression models were used to examine outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 10,422,242 newborn hospitalizations in 2020 through 2022, 15,300 were diagnosed with cleft lip and\/or palate (CLP). During this period, the in-hospital mortality rate was significantly higher among newborns with CLP (3.9%) compared to those without CLP (0.03%). Hospitalization charges for newborns with CLP were substantially higher than those without CLP (mean charges of $106,617 versus $22,671). The average LOS in those with CLP was 10.5 days compared to 3.4 days in those without CLP. In-hospital mortality, LOS, and hospital charges were significantly higher in newborns with CLP compared to those without CLP after controlling for potential confounders (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The overall incidence rate of CLP among hospitalized newborns was 1.468 per 1000 newborns during the study period. Following controlling for a variety of patient and hospital-related variables, in-hospital mortality rate, LOS, and hospital charges were significantly higher among newborns with CLP compared to those without CLP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656251388715","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:08:27Z","timestamp":1761581307000},"page":"2769-2778","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Association Between Cleft Lip and or Palate and Hospitalization Outcomes Among Newborns in the United States"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3913-6039","authenticated-orcid":false,"given":"Bushra","family":"Kanwal","sequence":"first","affiliation":[{"name":"University of Illinois Chicago College of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veerasathpurush","family":"Allareddy","sequence":"additional","affiliation":[{"name":"University of Illinois Chicago College of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Han","sequence":"additional","affiliation":[{"name":"University of Illinois Chicago College of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed H.","family":"Elnagar","sequence":"additional","affiliation":[{"name":"University of Illinois Chicago College of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Ahn","sequence":"additional","affiliation":[{"name":"University of Illinois Chicago College of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofie","family":"Vogel","sequence":"additional","affiliation":[{"name":"University of Illinois Chicago College of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shankar R.","family":"Venugopalan","sequence":"additional","affiliation":[{"name":"Tufts University School of Dental Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maysaa","family":"Oubaidin","sequence":"additional","affiliation":[{"name":"University of Illinois Chicago College of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Kyeong","family":"Lee","sequence":"additional","affiliation":[{"name":"University of Illinois Chicago College of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,27]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddw104"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2933"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2020.01.001"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/14767050500072854"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1597\/11-087"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38106.559120.7C"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/1055665617726531"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2011.07.026"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182043af6"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.28077"},{"key":"e_1_3_2_12_2","doi-asserted-by":"crossref","unstructured":"What Does Cleft Lip and Palate Care Cost?. 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