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Juho Suojanen research group"]}],"id":[{"id":"https:\/\/ror.org\/02e8hzf44","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005634","name":"Suomen Hammasl\u00e4\u00e4k\u00e4riseura Apollonia","doi-asserted-by":"publisher","award":["20240075"],"award-info":[{"award-number":["20240075"]}],"id":[{"id":"10.13039\/501100005634","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To cephalometrically compare craniofacial morphology and maxillary advancement in growing versus non-growing patients with clefts undergoing Le Fort I osteotomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>All patients underwent maxillary osteotomy at a single tertiary hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>The Pre-Growth-Completion group (PreGC) comprised 28 growing patients (18 males, 10 females; 9 BCLP, 18 UCLP, 1 CP) with a mean age at surgery of 13.5 years (SD\u2009=\u20091.22; range, 11.5-16.7). The Post-Growth-Completion group (PostGC) comprised 59 patients (28 males, 31 females; 15 BCLP, 23 UCLP, 21 CP) with a mean age at surgery of 18.3 years (SD\u2009=\u20094.38; range, 14.5-45.3). Patients with syndromes and those undergoing bimaxillary osteotomies were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Each patient underwent Le Fort I osteotomy. Osteotomies were fixed with patient-specific implants or miniplates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Cephalometric analysis was performed comparing preoperative lateral cephalometric radiographs or CT scans and immediate postoperative lateral cephalometric radiographs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients in PreGC group had more severe preoperative maxillary hypoplasia (SNA 74.2\u00b0 vs 77.0\u00b0,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.007; ANB \u22125.2\u00b0 vs \u22121.9\u00b0,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.0001), but no significant differences were observed postoperatively (SNA 80.7\u00b0 vs 78.9\u00b0, ANB 2.7\u00b0 vs 3.9\u00b0). Maxillary horizontal advancement was greater in the PreGC group (point A 6.4\u2005mm vs 3.2\u2005mm;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.00002).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients undergoing early Le Fort I osteotomy had more severe preoperative maxillary hypoplasia, required greater horizontal advancements, yet achieved significant corrections comparable to patients treated later. However, early osteotomy in growing patients may be considered a 2-stage approach as secondary correction is often required after growth is complete.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656261424586","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T16:44:31Z","timestamp":1772037871000},"page":"3931-3940","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cephalometric Comparison of Le Fort I Osteotomy in Growing and Non-Growing Patients With Clefts: A Retrospective Study"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4459-0359","authenticated-orcid":false,"given":"Minna","family":"Merta","sequence":"first","affiliation":[{"name":"P\u00e4ij\u00e4t-H\u00e4me Joint Authority for Health and Wellbeing"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roni","family":"Harjunp\u00e4\u00e4","sequence":"additional","affiliation":[{"name":"Helsinki University Hospital and Helsinki University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junnu","family":"Leikola","sequence":"additional","affiliation":[{"name":"Helsinki University Hospital and Helsinki University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juho","family":"Suojanen","sequence":"additional","affiliation":[{"name":"P\u00e4ij\u00e4t-H\u00e4me Joint Authority for Health and Wellbeing"},{"name":"Helsinki University Hospital and Helsinki University"},{"name":"University of Helsinki"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora","family":"Holmberg","sequence":"additional","affiliation":[{"name":"Helsinki University Hospital and Helsinki University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8064-3484","authenticated-orcid":false,"given":"Arja","family":"Heli\u00f6vaara","sequence":"additional","affiliation":[{"name":"Helsinki University Hospital and Helsinki University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0889-5406(86)90022-3"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjz070"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/22.6.697"},{"key":"e_1_3_3_5_2","first-page":"28","volume-title":"Facial clefts and craniosynostosis principles and management","author":"Semb GS","year":"1996","unstructured":"Semb GS, Shaw WC. 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