{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T11:58:40Z","timestamp":1791547120255,"version":"4.3.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,11]]},"abstract":"\n Objective<\/jats:title>\n The objective of this study was to evaluate the efficacy of the suprazygomatic maxillary nerve block in reducing postoperative inpatient opioid requirements in patients undergoing palatoplasty for cleft palate repair.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Retrospective cohort study<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Tertiary care children's hospital<\/jats:p>\n <\/jats:sec>\n \n Patients, Participants<\/jats:title>\n Patients with isolated cleft palate or cleft lip and palate who underwent palatoplasty at our institution between 2006 and 2025.<\/jats:p>\n <\/jats:sec>\n \n Interventions<\/jats:title>\n \n Patients who received the suprazygomatic maxillary nerve block and a controlled cohort of patients who underwent cleft palate repair during the same time period without receiving a nerve block were assessed. Patient demographics, perioperative data, and opioid requirements within the immediate eight hours (in morphine milliequivalents [MME]) following surgery were recorded. Multivariate regression analysis was performed, with significance defined as\n p<\/jats:italic>\n \u2009<\u2009.05.\n <\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measures<\/jats:title>\n Inpatient opioid requirement eight hours following surgery<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 470 patients were included, with 235 (50.0%) in the nerve block group and 235 (50.0%) in the group without nerve block. When adjusting for age, sex, Veau class, and surgical approach, use of nerve block was associated with a significantly lower amount of MME administered in the first eight hours following palatoplasty (OR\u2009=\u20090.54, 95% CI [0.34\u20130.87],\n p<\/jats:italic>\n \u2009=\u2009.011).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The suprazygomatic maxillary nerve block appears to be an effective technique for reducing postoperative inpatient opioid requirements in children undergoing cleft palate repair.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/10556656261429798","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T09:23:02Z","timestamp":1773307382000},"page":"3817-3821","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Suprazygomatic Maxillary Nerve Block is Associated with Reduced Postoperative Inpatient Opioid Requirement in Patients Undergoing Palatoplasty"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0088-2991","authenticated-orcid":false,"given":"Artur","family":"Manasyan","sequence":"first","affiliation":[{"name":"Children's Hospital Los Angeles"},{"name":"Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Donaldson","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka","family":"Naidu","sequence":"additional","affiliation":[{"name":"Children's Hospital Los Angeles"},{"name":"Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diba","family":"Nayeri","sequence":"additional","affiliation":[{"name":"Children's Hospital Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark M.","family":"Urata","sequence":"additional","affiliation":[{"name":"Children's Hospital Los Angeles"},{"name":"Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0030-1420","authenticated-orcid":false,"given":"Jeffrey A.","family":"Hammoudeh","sequence":"additional","affiliation":[{"name":"Children's Hospital Los Angeles"},{"name":"Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7292-2432","authenticated-orcid":false,"suffix":"III","given":"William P.","family":"Magee","sequence":"additional","affiliation":[{"name":"Children's Hospital Los Angeles"},{"name":"Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"key":"e_1_3_2_2_2","volume-title":"StatPearls","author":"Puente Espel J","year":"2023","unstructured":"Puente Espel J, Hohman MH, Winters R. Cleft palate repair. In: StatPearls. Tampa, FL: StatPearls Publishing; 2023."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jobcr.2023.02.003"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2015.06.007"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000006985"},{"issue":"1","key":"e_1_3_2_6_2","article-title":"Is the use of opioids safe after primary cleft palate repair? A systematic review","volume":"9","author":"Rossell-Perry P","year":"2021","unstructured":"Rossell-Perry P, Romero-Narvaez C, Rojas-Sandoval R, Gomez-Henao P, Delgado-Jimenez MP, Marca-Ticona R. Is the use of opioids safe after primary cleft palate repair? A systematic review. Plast Reconstr Surg Glob Open. 2021;9(1):e3355.","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000009498"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12660"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003549"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2017.0504"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005193"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000009231"},{"key":"e_1_3_2_13_2","volume-title":"StatPearls","author":"Ghlichloo I","year":"2023","unstructured":"Ghlichloo I, Gerriets V. Nonsteroidal anti-inflammatory drugs (NSAIDs). In: StatPearls. Tampa, FL: StatPearls Publishing; 2023."},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2010.03262.x"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.5603\/FM.2015.0025"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2011.09.007"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.3390\/ph18101429"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-023-02291-x"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2024.1011"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2012.03861.x"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000171"},{"key":"e_1_3_2_22_2","doi-asserted-by":"crossref","unstructured":"Garcia Nores GD Cuzzone DA Hush SE Pandya K Stuart A Williams JK Brady CM. The impact of bilateral suprazygomatic maxillary nerve blocks on postoperative pain control in patients undergoing orthognathic surgery. FACE. Published online August 11 2020.","DOI":"10.1177\/2732501620949188"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000001585"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.21.00045"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/XCS.0000000000000109"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/PTS.0000000000000566"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeh180"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-024086"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-2439"}],"container-title":["The Cleft Palate Craniofacial Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10556656261429798","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10556656261429798","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10556656261429798","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T11:48:01Z","timestamp":1791546481000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10556656261429798"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,12]]},"references-count":28,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1177\/10556656261429798"],"URL":"https:\/\/doi.org\/10.1177\/10556656261429798","relation":{},"ISSN":["1055-6656","1545-1569"],"issn-type":[{"value":"1055-6656","type":"print"},{"value":"1545-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,12]]}}}