{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:34:23Z","timestamp":1792787663679,"version":"4.5.0"},"reference-count":46,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"International Orthodontics Foundation","award":["IOF2023Y40"],"award-info":[{"award-number":["IOF2023Y40"]}]},{"name":"the Smile Train","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"https:\/\/ror.org\/00x94td80","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate long-term effects of presurgical nasoalveolar molding (PNAM) on occlusal relationships and craniofacial development in children with unilateral cleft lip and palate (UCLP) using the 5-year-olds\u2019 index and cone-beam computed tomography (CBCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary-level Class A specialized stomatological hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Sixty-four patients with complete UCLP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Thirty patients underwent PNAM treatment, and 34 patients did not.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure<\/jats:title>\n                    <jats:p>\n                      CBCT scans were used to assess dental occlusion via the 5-year-old index and to measure craniofacial variables. Intergroup differences were analyzed using the Mann\u2013Whitney\n                      <jats:italic toggle=\"yes\">U<\/jats:italic>\n                      test and the chi-square test, while the correlation between occlusion and craniofacial variables was examined using the Pearson correlation coefficient. A\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value of less than .05 was considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A comparison of 5-year-olds\u2019 index scores in the two groups showed median scores of 3.0 (PNAM group) and 3.5 (non-PNAM group), respectively, with no significant difference found. For prognosis, no significant difference in orthognathic surgery need was found, but the PNAM group had a higher nonsurgery rate (60%) versus 50% in the non-PNAM group. In craniofacial development, the PNAM group had significantly longer maxillary length; favorable prognosis group showed smaller SNB angles, shorter mandibular body, larger ANB angles, and longer maxillary length. Correlation analysis showed 5-year-olds\u2019 index positively correlated with SNB\/mandibular body length, and negatively with ANB\/maxillary length.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Early childhood evaluations showed that treatment with\/without PNAM in the neonatal period was not a major factor influencing occlusal relationships or craniofacial development in patients with UCLP. Furthermore, correlation between 5-year-olds\u2019 index and skeletal morphology in children with UCLP has been confirmed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656261429897","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T09:23:40Z","timestamp":1773307420000},"page":"3775-3786","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Dental Relationship and Craniofacial Development in Children With Unilateral Cleft Lip and Palate Treated With\/Without Presurgical Nasoalveolar Molding"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9791-855X","authenticated-orcid":false,"given":"Jie","family":"Zheng","sequence":"first","affiliation":[{"name":"School & Hospital of Stomatology, Wuhan University"},{"name":"Department of Orthodontics, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, People's Republic of China"},{"name":"Hubei Provincial Clinical Research Center for Dentofacial Deformities in Children, School &amp; Hospital of Stomatology, Wuhan University, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiqing","family":"Ren","sequence":"additional","affiliation":[{"name":"School & Hospital of Stomatology, Wuhan University"},{"name":"Chongqing Hospital, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Chongqing, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengkun","family":"Yang","sequence":"additional","affiliation":[{"name":"School & Hospital of Stomatology, Wuhan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangqi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7239-3398","authenticated-orcid":false,"given":"Wenjun","family":"Yuan","sequence":"additional","affiliation":[{"name":"School & Hospital of Stomatology, Wuhan University"},{"name":"Department of Orthodontics, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, People's Republic of China"},{"name":"Hubei Provincial Clinical Research Center for Dentofacial Deformities in Children, School &amp; Hospital of Stomatology, Wuhan University, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000008296"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.2319\/091919-598.1"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2017.03.006"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1999_036_0486_pnmiiw_2.3.co_2"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sodo.2025.08.004"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sodo.2025.09.011"},{"issue":"3","key":"e_1_3_2_8_2","first-page":"91","article-title":"The influence of early orthodontic treatment on the growth of craniofacial complex in deciduous occlusion of unilateral cleft lip and palate patients","volume":"9","author":"Maulina I","year":"2007","unstructured":"Maulina I, Priede D, Linkeviciene L, Akota I. 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