{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T14:40:53Z","timestamp":1793716853380,"version":"4.6.1"},"reference-count":31,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the potential impact of a history of cleft lip and\/or palate (CL\/P) on medial olivocochlear (MOC) efferent system modulation in children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross-sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>University-affiliated audiology research laboratory under controlled acoustic conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Fifty-two children aged 9 to 15 years with typical hearing participated, including 26 children with surgically repaired, non-syndromic CL\/P (CL\/P group) and 26 typically developing peers (control group).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>MOC modulation was assessed using a dual-probe, linear-mode protocol with the Otodynamics ILO292-II system. Transient-evoked otoacoustic emissions (TEOAEs) were recorded in quiet at 1, 1.5, 2, 3, and 4\u2005kHz using a 65\u2005dB peSPL stimulus. Contralateral suppression of TEOAEs was subsequently measured at the same frequencies by presenting 65\u2005dB SPL broadband noise to the contralateral ear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>TEOAE amplitudes and contralateral suppression amplitudes across the 1 to 4\u2005kHz frequency range.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The CL\/P group exhibited significantly reduced TEOAE amplitudes and significantly lower contralateral suppression amplitudes across the entire 1 to 4\u2005kHz frequency range compared with the control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results suggest that typically hearing children with a history of CL\/P may show subtle differences in cochlear output and MOC efferent modulation, potentially associated with early life auditory challenges. The observed MOC modulation differences may be partially influenced by reduced TEOAE amplitudes and\/or reflect independent efferent regulatory mechanisms. Further investigation is required to clarify the relative contributions of these factors and their potential functional implications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656261446655","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:01:58Z","timestamp":1777906918000},"page":"4167-4172","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Medial Olivocochlear Modulation in Children With Cleft Lip and Palate: Evidence From Contralateral Suppression of TEOAEs"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2846-642X","authenticated-orcid":false,"given":"Fatma","family":"Yurdakul \u00c7\u0131nar","sequence":"first","affiliation":[{"name":"Inonu University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjpo-2023-002305"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.59227"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.4103\/jclpca.jclpca_12_22"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otoeng.2020.11.005"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2182-22.2023"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/10.7.714"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348947908800515"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.12.021"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.2383"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1250-8639"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-024-04804-7"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000883"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcomdis.2020.106029"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/10556656241290732"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2020.109915"},{"issue":"1","key":"e_1_3_3_17_2","first-page":"20","article-title":"Evaluation of medial olivocochlear neural efferent pathway in tinnitus perception in normal-hearing individuals","volume":"26","author":"Tayade A","year":"2022","unstructured":"Tayade A, Tucker D. Evaluation of medial olivocochlear neural efferent pathway in tinnitus perception in normal-hearing individuals. Int Tinnitus J. 2022;26(1):20\u201326.","journal-title":"Int Tinnitus J"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1997.77.4.1759"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12134553"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199705060-00042"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2021.108207"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1044\/sha.2307.493"},{"key":"e_1_3_3_23_2","volume-title":"Handbook of Clinical Audiology. 7th ed","author":"Katz J","year":"2015","unstructured":"Katz J, Chasin M, English K, Hood LJ, Tillery KL. Basic tests and procedures. In: Katz J, ed. Handbook of Clinical Audiology. 7th ed. 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