{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T12:17:49Z","timestamp":1783253869797,"version":"3.54.6"},"reference-count":31,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"abstract":"\n Objective<\/jats:title>\n To compare maxillary bone structure between right- and left-sided unilateral cleft lip and palate (UCLP), quantify cleft vs. non-cleft asymmetry, and determine whether the non-cleft side differs from healthy controls.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Retrospective cross-sectional cohort study.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n University hospital, Department of Oral and Dentomaxillofacial Radiology.<\/jats:p>\n <\/jats:sec>\n \n Patients, Participants<\/jats:title>\n Fifty UCLP (25 right, 25 left; mean age 14.8\u2009\u00b1\u20095.1 years) and 50 controls (16.5\u2009\u00b1\u20094.6 years). Power calculation indicated n\u2009=\u200928\/group sufficient.<\/jats:p>\n <\/jats:sec>\n \n Interventions<\/jats:title>\n Cortical thickness measured on CBCT at 4-12\u2005mm depth across 6 interradicular regions. Trabecular architecture assessed by fractal dimension (FD) (BoneJ\/Fiji).<\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measures<\/jats:title>\n Cortical thickness and FD differences between right-\/left-UCLP, cleft vs. non-cleft sides, non-cleft vs. controls.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n No differences between right- and left-UCLP cleft sides (\n P<\/jats:italic>\n \u2009>\u20090.05). Cleft side thickness was 0.05-0.07\u2005mm less than non-cleft side in anterior regions (\n P<\/jats:italic>\n \u2009<\u20090.001, d\u2009=\u20090.30-0.38). Non-cleft side was thinner than controls by 0.12-0.18\u2005mm (\n P<\/jats:italic>\n \u2009<\u20090.001), representing 86-92% of control thickness. FD showed similar patterns. Asymmetry increased from posterior to anterior.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n UCLP is associated with bilateral maxillary bone deficits; the non-cleft side also shows significant deviations from controls. Side-specific assessment is essential. These differences may warrant caution in treatment planning, but prospective outcome studies are needed.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/10556656261465481","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T10:54:34Z","timestamp":1783076074000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Asymmetry of Maxillary Bone Structure in Unilateral Cleft Lip and Palate: A Cone Beam Computed Tomography Study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9800-7195","authenticated-orcid":false,"given":"Murat Mert","family":"Atapek","sequence":"first","affiliation":[{"name":"Yeditepe University Faculty of Dentistry"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000004359"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/ijos.2014.59"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-020-00276-w"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14222555"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2353(2000)13:2<121::AID-CA6>3.0.CO;2-K"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.2319\/061614-438.1"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1756137"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.12688\/wellcomeopenres.16619.1"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14192143"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.15-0609"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.5455\/aim.2020.28.272-277"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1597\/10-044"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2024.04.020"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-023-05119-7"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-024-05067-y"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2019"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2018.01.008"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10024-3343"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(96)80205-8"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11282-024-00756-4"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02246.x"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.587859"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-023-02714-8"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2011.01468.x"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40510-016-0127-z"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1179\/bjo.4.2.53"},{"issue":"3","key":"e_1_3_2_28_2","first-page":"78","article-title":"Family history and risk factors for cleft lip and palate patients and their associated anomalies","volume":"19","author":"Jamilian A","year":"2017","unstructured":"Jamilian A, Sarkarat F, Jafari M, Neshandar M, Amini E, Khosravi S, Ghassemi A. Family history and risk factors for cleft lip and palate patients and their associated anomalies. 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