{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T14:10:32Z","timestamp":1789567832628,"version":"build-2803163510"},"reference-count":43,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the efficacy of the premaxilla manipulation technique (PMT) for fast correction of deviated and rotated premaxilla.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective cohort study with repeated measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary cleft and craniofacial center within an academic institution\/hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Nine non-syndromic neonates with bilateral cleft lip and palate (BCLP) presenting for management of deviated, rotated, and protruded premaxilla.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Nasoalveolar molding (NAM) therapy after one-step PMT during impression-taking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Resolution of deviation, rotation, and protrusion of the premaxilla measured by angular photogrammetry using ImageJ software on standardized photographs taken at 4 different timepoints, T0 (beginning), T1 (1-2 weeks), T2 (1 month), and T3 (before cheiloplasty).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No adverse events occurred during NAM therapy (mean duration: 80.85\u2009\u00b1\u200924.18 days), which began at a mean infant age of 17.5\u2009\u00b1\u20098.19 days. Reliability of photogrammetry was high (intraclass correlation coefficient r\u2009=\u20090.890,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001). Premaxillary deviation and rotation demonstrated significant immediate correction by T1 (12\u2009\u00b1\u20096.09 days), decreasing from 18.28\u00b0 to \u22122.43\u00b0 and 19.34\u00b0 to 3.56\u00b0, respectively (both False Discovery Rate-adjusted\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.015), and stabilizing thereafter. Conversely, premaxillary protrusion exhibited a continuous, stepwise reduction across all intervals, decreasing significantly from 40.16\u00b0 at T0 to 32.27\u00b0 at T1 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.012) and continued to improve significantly through T3.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The PMT suggests potential effectiveness in correcting the premaxillary deviation and rotation in infants with BCLP. The limitations of small sample size due to the preliminary nature of the study and 2D photogrammetry call for a long-term clinical trial comparing techniques utilizing 3D imaging.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656261488098","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T04:20:02Z","timestamp":1789446002000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Premaxilla Manipulation Technique for Molding Deviated and Rotated Premaxilla in Bilateral Cleft Lip Palate Neonates: A Preliminary Study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7367-3642","authenticated-orcid":false,"given":"Navdeep","family":"Bhusri","sequence":"first","affiliation":[{"name":"University of Alabama at Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0370-8608","authenticated-orcid":false,"given":"Mohammad","family":"Zeinalddin","sequence":"additional","affiliation":[{"name":"Mohammad Orthodontic Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6152-0921","authenticated-orcid":false,"given":"Eric JW","family":"Liou","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital"},{"name":"Graduate Institute of Craniofacial and Dental Science, Chang Gung University, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archfami.7.1.88"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-004-1127-8"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000002167"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000003517"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000001430"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198401000-00009"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198901000-00006"},{"issue":"7","key":"e_1_3_2_9_2","first-page":"1422","article-title":"Preoperative columella lengthening in bilateral cleft lip and palate","volume":"92","author":"Grayson BH","year":"1993","unstructured":"Grayson BH, Cutting C, Wood R. 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