{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:59:49Z","timestamp":1790391589595,"version":"4.1.0"},"reference-count":38,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Cleft Palate Craniofacial Journal"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare oral health-related quality of life (OHRQoL) of individuals with cleft lip and palate (CLP) and skeletal Class III malocclusion before and 6 months after orthognathic surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Longitudinal observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Fifty-two individuals with CLP and skeletal Class III malocclusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Orthognathic surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcomes<\/jats:title>\n                    <jats:p>Changes in OHIP-14 (oral health impact profile-14) score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among individuals included, 30 (58%) were female, 28 (54%) were \u2264 21 years old, 36 (69%) were \u201cWhite,\u201d 30 (58%) presented with facial asymmetry, and 38 (73%) had unilateral CLP. Analyses using the Wilcoxon test and the Mann\u2013Whitney\n                      <jats:italic toggle=\"yes\">U<\/jats:italic>\n                      test indicated improvement in OHRQoL. The total OHIP-14 score improved significantly (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.002), along with the domains of \u201cpsychological discomfort\u201d (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.015), \u201cpsychological disability\u201d (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.002), \u201csocial disability\u201d (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001), and \u201cparticipant restriction\u201d (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The term \u201cparticipant restriction\u201d has been used to supersede the original domain terminology \u201chandicap\u201d. Exploratory within-subgroup analyses indicated reductions in OHIP-14 scores among females (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.007), individuals older than 21 years (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.008), self-reported \u201cWhite\u201d participants (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.008), those with facial asymmetry (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.013), and both unilateral (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.034) and bilateral CLP (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.024) phenotypes. However, these within-group changes are exploratory and do not establish significant differences in treatment effect between subgroups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Orthognathic surgery improved the OHRQoL in individuals with non-syndromic CLP and skeletal Class III malocclusion. Improvements were observed in the total OHIP-14 score and in psychological, social, and participation restriction domains related to OHRQoL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10556656261492412","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:16:04Z","timestamp":1790075764000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Orthognathic Surgery and Oral Health-Related Quality of Life in Skeletal Class III Non-Syndromic Patients with Cleft Lip and Palate"],"prefix":"10.1177","author":[{"given":"Bernardo","family":"Olsson","sequence":"first","affiliation":[{"name":"Federal University of Paran\u00e1"},{"name":"Cleft Lip and Palate Integral Care Center, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Fanderuff","sequence":"additional","affiliation":[{"name":"Federal University of Paran\u00e1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katheleen Miranda","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Federal University of Paran\u00e1"},{"name":"Cleft Lip and Palate Integral Care Center, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delson Joao da","family":"Costa","sequence":"additional","affiliation":[{"name":"Federal University of Paran\u00e1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline Monise","family":"Sebastiani","sequence":"additional","affiliation":[{"name":"Federal University of Paran\u00e1"},{"name":"Cleft Lip and Palate Integral Care Center, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4911-6413","authenticated-orcid":false,"given":"Rafaela","family":"Scariot","sequence":"additional","affiliation":[{"name":"Federal University of Paran\u00e1"},{"name":"Cleft Lip and Palate Integral Care Center, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1590\/1806-93042019000400012"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1922\/CDH_3225Antonarakis07"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1996_033_0051_iiolap_2.3.co_2"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2018.09.018"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1597\/13-104"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-023-03382-4"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2018.08.013"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2020.08.014"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjab039"},{"key":"e_1_3_3_11_2","unstructured":"BRASIL. 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