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This study assessed the outcomes of an e-cigarette prevention program with teachers and parents\/guardians across a three-county rural area. Researchers assessed teachers\u2019 and parent\/guardians\u2019 increased knowledge and confidence in implementing vape prevention after receiving evidence-based trainings. Pre- and post-surveys demonstrated that teachers had a statistically significant increase in knowledge gain across all eight vape-specific domains assessed as expected. The parent\/guardian pre- and post-survey results also show that knowledge and confidence increased significantly across seven domains. Findings suggest that multicomponent e-cigarette education and prevention programs better prepare teachers and parents\/guardians to intervene with youth e-cigarette use and initiation, including being more likely to talk to youth about the risks of tobacco and vaping. Recommendations for school nurses are discussed and include educating youth, families, and staff for positive impacts.<\/jats:p>","DOI":"10.1177\/10598405231198020","type":"journal-article","created":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T07:18:44Z","timestamp":1693379924000},"page":"535-547","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating a Multicomponent e-Cigarette Prevention Program in the Rural Northwest: Teacher and Parent\/Guardian Program Outcomes"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6332-7922","authenticated-orcid":false,"given":"Ashley C.","family":"Yaugher","sequence":"first","affiliation":[{"name":"Utah State University, Cooperative Extension in Carbon, Emery, and Grand Counties"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina C.","family":"Pay","sequence":"additional","affiliation":[{"name":"Utah State University, Cooperative Extension in Carbon, Emery, and Grand Counties"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenna","family":"Hawks","sequence":"additional","affiliation":[{"name":"Utah State University, Cooperative Extension in Carbon, Emery, and Grand Counties"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6328-4272","authenticated-orcid":false,"given":"Cristian L.","family":"Meier","sequence":"additional","affiliation":[{"name":"Utah State University, Cooperative Extension in Carbon, Emery, and Grand Counties"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,8,30]]},"reference":[{"key":"e_1_3_3_2_1","unstructured":"American Lung Association. 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