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Mental health of high school students has predominantly been the focus in literature with less emphasis on younger adolescents. This review identified articles published in the last decade that described evaluations of middle school-based mental health interventions and randomized participants to an intervention or control condition. Fourteen interventions met the inclusion criteria. About two-thirds of interventions were based on mindfulness or cognitive behavioral therapy. Many trials utilized racially diverse, low-income samples. All interventions were delivered to groups, and three contained a parent component. Five trials increased rigor by using an active control condition. Almost two-thirds of the interventions were effective (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u2009.10) in reducing at least one depression, anxiety, affect, or internalizing symptom outcome compared to a control group. This article provides information about intervention characteristics, efficacy, theoretical framework, and acceptability\/feasibility.\n                  <\/jats:p>","DOI":"10.1177\/10598405241265904","type":"journal-article","created":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T00:00:25Z","timestamp":1722556825000},"page":"56-74","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Mental Health Interventions in Middle Schools: A 10-Year Review of Research"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9409-1537","authenticated-orcid":false,"given":"Elizabeth Anne","family":"McKay","sequence":"first","affiliation":[{"name":"University of Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Mattheus","sequence":"additional","affiliation":[{"name":"Nancy Atmospera-Walch School of Nursing, University of Hawaii at Manoa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holly B.","family":"Fontenot","sequence":"additional","affiliation":[{"name":"Nancy Atmospera-Walch School of Nursing, University of Hawaii at Manoa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,8]]},"reference":[{"key":"e_1_3_2_2_1","unstructured":"American Academy of Pediatrics. 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