{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:16:55Z","timestamp":1777418215815,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Pharmacother"],"published-print":{"date-parts":[[2003,2]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To assess the clinical literature describing the use of ivermectin in cases of treatment-resistant scabies infestations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SOURCES:<\/jats:title>\n                    <jats:p>Clinical literature accessed through a MEDLINE search (1966\u2013July 2001) and the Cochrane Database.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SYNTHESIS:<\/jats:title>\n                    <jats:p>A limited number of case reports and case series describes successful intervention with ivermectin use in patients who have failed prior therapy. Ivermectin may serve as a viable alternative therapy as the incidence of resistant scabitic infestations increases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Ivermectin appears to be a safe and effective alternative for patients with treatment-resistant scabies. Larger, controlled clinical trials are required before this therapy can be recommended in the general population or as primary therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/106002800303700221","type":"journal-article","created":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T07:39:55Z","timestamp":1483688395000},"page":"279-281","source":"Crossref","is-referenced-by-count":2,"title":["Ivermectin for the Treatment of Resistant Scabies"],"prefix":"10.1177","volume":"37","author":[{"given":"Aaron M","family":"Cook","sequence":"first","affiliation":[{"name":"Aaron M Cook PharmD, Surgery\/Critical Care Clinical Specialist, University of Texas Medical Branch, Galveston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Romanelli","sequence":"additional","affiliation":[{"name":"Frank Romanelli PharmD BCPS, Assistant Professor, Clinical Specialist in HIV, College of Pharmacy, University of Kentucky, Lexington, KY"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,2,1]]},"reference":[{"key":"bibr1-106002800303700221","first-page":"233","volume":"65","author":"Burkhart CG","year":"2000","journal-title":"Cutis"},{"key":"bibr2-106002800303700221","first-page":"443","volume":"9","author":"Dannaoui E","year":"1999","journal-title":"Eur J Dermatol"},{"key":"bibr3-106002800303700221","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000320"},{"key":"bibr4-106002800303700221","doi-asserted-by":"publisher","DOI":"10.1016\/S1201-9712(98)90118-7"},{"key":"bibr5-106002800303700221","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.1999.016001069.x"},{"key":"bibr6-106002800303700221","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.6.651"},{"key":"bibr7-106002800303700221","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199507063330105"},{"key":"bibr8-106002800303700221","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90131-2"},{"key":"bibr9-106002800303700221","volume-title":"Package insert. 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