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Options for pharmacological stress test agents include adenosine, regadenoson, dipyridamole, and dobutamine, whereas aminophylline is the recommended reversal agent. Adenosine and dobutamine can be used as alternatives to regadenoson and dipyridamole to decrease or eliminate the use of aminophylline. Alternatives to aminophylline include theophylline and caffeine. It is important to efficiently identify alternatives during a drug shortage to maintain optimal patient outcomes.<\/jats:p>","DOI":"10.1177\/1060028018806624","type":"journal-article","created":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T03:10:05Z","timestamp":1539227405000},"page":"316-320","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Theophylline and Caffeine as Alternatives During an Aminophylline Shortage"],"prefix":"10.1177","volume":"53","author":[{"given":"Emily L.","family":"Singleton","sequence":"first","affiliation":[{"name":"Belmont University College of Pharmacy, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Le","sequence":"additional","affiliation":[{"name":"Belmont University College of Pharmacy, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevieve Lynn","family":"Ness","sequence":"additional","affiliation":[{"name":"Belmont University College of Pharmacy, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,10,11]]},"reference":[{"key":"bibr1-1060028018806624","unstructured":"US Food and Drug Administration. 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