{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:09:43Z","timestamp":1777421383620,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:00:00Z","timestamp":1640649600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100009655","name":"Sunovion","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009655","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ann Pharmacother"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Assessing chronic obstructive pulmonary disease (COPD) severity is challenging in nursing home (NH) residents due to incomplete symptom assessments and exacerbation history.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study was to predict COPD severity in NH residents using the Minimum Data Set (MDS), a clinical assessment of functional capabilities and health needs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cohort analysis of prospectively collected longitudinal data was conducted. Residents from geographically varied Medicare-certified NHs with age \u226560 years, COPD diagnosis, and \u22656 months NH residence at enrollment were included. Residents with severe cognitive impairment were excluded. Demographic characteristics, medical history, and MDS variables were extracted from medical records. The care provider\u2013completed COPD Assessment Test (CAT) and COPD exacerbation history were used to categorize residents by Global Initiative for Chronic Lung Disease (GOLD) A to D groups. Multivariate multinomial logit models mapped the MDS to GOLD A to D groups with stepwise selection of variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nursing home residents (N = 175) were 64% women and had a mean age of 77.9 years. Among residents, GOLD B was most common (A = 13.1%; B = 44.0%; C = 5.7%; D = 37.1%). Any long-acting bronchodilator (LABD) use and any dyspnea were significant predictors of GOLD A to D groups. The predicted MDS-GOLD group (A = 6.9%; B = 52.6%; C = 4.6%; D = 36.0%) showed good model fit (correctly predicted = 60.6%). Nursing home residents may underuse group-recommended LABD treatment (no LABD: B = 53.2%; C = 80.0%; D = 40.0%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Relevance<\/jats:title>\n                    <jats:p>The MDS, completed routinely for US NH residents, could potentially be used to estimate COPD severity. Predicted COPD severity with additional validation could provide a map to evidence-based treatment guidelines and may help to individualize treatment pathways for NH residents.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10600280211059241","type":"journal-article","created":{"date-parts":[[2021,12,29]],"date-time":"2021-12-29T00:48:18Z","timestamp":1640738898000},"page":"878-887","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of MDS-Based Predication Model for COPD Severity in Nursing Home Residents"],"prefix":"10.1177","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2063-1796","authenticated-orcid":false,"given":"Barbara","family":"Blaylock","sequence":"first","affiliation":[{"name":"Blaylock Health Economics LLC, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Niu","sequence":"additional","affiliation":[{"name":"Health Economics and Outcomes Research, Sunovion Pharmaceuticals Inc., Marlborough, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. Edward","family":"Davidson","sequence":"additional","affiliation":[{"name":"Insight Therapeutics, LLC, Norfolk, VA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Gravenstein","sequence":"additional","affiliation":[{"name":"Department of Health Services, Policy and Practice, Center for Gerontology and Health Care Research, Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"DePue","sequence":"additional","affiliation":[{"name":"Health Economics and Outcomes Research, Sunovion Pharmaceuticals Inc., Marlborough, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Rhys","family":"Williams","sequence":"additional","affiliation":[{"name":"Health Economics and Outcomes Research, Sunovion Pharmaceuticals Inc., Marlborough, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl E.","family":"Steinberg","sequence":"additional","affiliation":[{"name":"Shiley Institute for Palliative Care, The California State University, San Marcos, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,12,28]]},"reference":[{"key":"bibr1-10600280211059241","unstructured":"Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease\u20142020 report. Accessed March 27, 2020. https:\/\/goldcopd.org\/wp-content\/uploads\/2019\/12\/GOLD-2020-FINAL-ver1.2-03Dec19_WMV.pdf."},{"key":"bibr2-10600280211059241","unstructured":"National Institutes of Health. Morbidity and mortality: 2012 chart book on cardiovascular, lung, and blood diseases. Accessed August 3, 2021. https:\/\/www.nhlbi.nih.gov\/files\/docs\/research\/2012_ChartBook_508.pdf."},{"key":"bibr3-10600280211059241","unstructured":"National Center for Health Statistics. Health, United States, 2018. Accessed August 3, 2021. https:\/\/www.cdc.gov\/nchs\/data\/hus\/hus18.pdf."},{"key":"bibr4-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2020.09.255"},{"key":"bibr5-10600280211059241","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2012.18.8.598"},{"key":"bibr6-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(17)30235-7"},{"key":"bibr7-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-019-00680-x"},{"key":"bibr8-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjopharm.2009.11.003"},{"key":"bibr9-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2019.105857"},{"key":"bibr10-10600280211059241","unstructured":"AMDA -The Society for Post-Acute and Long-Term Care Medicine. Clinical practice guidelines: COPD management in the post-acute and long-term care setting. Accessed March 27, 2020. https:\/\/paltc.org\/product-store\/copd-management-cpg-pocket-guide."},{"key":"bibr11-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.1.249"},{"key":"bibr12-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1996.00440090084008"},{"key":"bibr13-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/32.3.299"},{"key":"bibr14-10600280211059241","doi-asserted-by":"publisher","DOI":"10.2147\/PI.S61200"},{"key":"bibr15-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0000000000000416"},{"key":"bibr16-10600280211059241","unstructured":"Centers for Medicare and Medicaid Services. MDS 3.0 frequency report. Accessed April 23, 2020. https:\/\/www.cms.gov\/Research-Statistics-Data-and-Systems\/Computer-Data-and-Systems\/Minimum-Data-Set-3-0-Public-Reports\/Minimum-Data-Set-3-0-Frequency-Report."},{"key":"bibr17-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-11-42"},{"key":"bibr18-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1177\/0898264314552419"},{"key":"bibr19-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-018-0932-9"},{"key":"bibr20-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gly044"},{"key":"bibr21-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2013.05.012"},{"key":"bibr22-10600280211059241","doi-asserted-by":"publisher","DOI":"10.4140\/TCP.n.2021.248"},{"key":"bibr23-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"bibr24-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/54.11.m546"},{"key":"bibr25-10600280211059241","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6722a4"},{"key":"bibr26-10600280211059241","doi-asserted-by":"publisher","DOI":"10.4324\/9780203771587"},{"key":"bibr27-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2018.07.010"},{"key":"bibr28-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2017.03.020"},{"key":"bibr29-10600280211059241","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2013.12.078"},{"key":"bibr30-10600280211059241","doi-asserted-by":"publisher","DOI":"10.4140\/TCP.n.2012.650"}],"container-title":["Annals of Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10600280211059241","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10600280211059241","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10600280211059241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:16:36Z","timestamp":1777374996000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10600280211059241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,28]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1177\/10600280211059241"],"URL":"https:\/\/doi.org\/10.1177\/10600280211059241","relation":{},"ISSN":["1060-0280","1542-6270"],"issn-type":[{"value":"1060-0280","type":"print"},{"value":"1542-6270","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,28]]}}}