{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:40:01Z","timestamp":1777416001182,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[1983,10,1]],"date-time":"1983-10-01T00:00:00Z","timestamp":433814400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug Intelligence &amp; Clinical Pharmacy"],"published-print":{"date-parts":[[1983,10]]},"abstract":"<jats:p>Neutropenia is rarely associated with cephalosporins. We report a case of neutropenia associated with cefotaxime.<\/jats:p>\n                  <jats:p>A seven-year-old boy was admitted to the Chidoribashi Hospital with suspected septicemia. Cefotaxime 2 g\/d was started. On day 18, neutropenia associated with cefotaxime was suspected. On day 22, the patient was transferred to Fukuoka Children's Hospital because of continuing neutropenia and eosinophilia.<\/jats:p>\n                  <jats:p>In Fukuoka Children's Hospital, bone marrow puncture revealed severe bone marrow depression. After one month, the patient was discharged. When we considered case reports of granulocytopenia, leukopenia, and agranulocytosis associated with cephalosporins, we found two types of leukopenia. One is the granulocytopenic type and the other is the neutropenic type. In diagnosing leukopenia due to cephalosporins, an increased percentage of eosinophils in white-blood-cell analysis is significant.<\/jats:p>","DOI":"10.1177\/106002808301701009","type":"journal-article","created":{"date-parts":[[2017,10,25]],"date-time":"2017-10-25T03:53:02Z","timestamp":1508903582000},"page":"739-741","source":"Crossref","is-referenced-by-count":7,"title":["Neutropenia Associated with Cefotaxime"],"prefix":"10.1177","volume":"17","author":[{"given":"Tomoji","family":"Ohsawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumitaka","family":"Furukawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,10,25]]},"reference":[{"key":"bibr1-106002808301701009","first-page":"174","volume":"28","author":"Watanabe A","year":"1980","journal-title":"Chemotherapy"},{"key":"bibr2-106002808301701009","first-page":"509","volume":"28","author":"Iwai N","year":"1980","journal-title":"Chemotherapy"},{"key":"bibr3-106002808301701009","first-page":"349","volume":"28","author":"Miki F","year":"1980","journal-title":"Chemotherapy"},{"key":"bibr4-106002808301701009","first-page":"228","volume":"28","author":"Shimizu K","year":"1980","journal-title":"Chemotherapy"},{"key":"bibr5-106002808301701009","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1093\/jac\/6.suppl_A.269","volume":"6","author":"Shah PM","year":"1980","journal-title":"J Antimicrob Chemother"},{"key":"bibr6-106002808301701009","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/jac\/6.suppl_A.293","volume":"6","author":"Young JPW","year":"1980","journal-title":"J Antimicrob Chemother"},{"key":"bibr7-106002808301701009","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/jac\/6.suppl_A.255","volume":"6","author":"Daikos GK","year":"1980","journal-title":"J Antimicrob Chemother"},{"key":"bibr8-106002808301701009","first-page":"650","volume":"10","author":"Kermarec J","year":"1981","journal-title":"Nouv Presse Med"},{"key":"bibr9-106002808301701009","first-page":"1529","volume":"32","author":"Itoh T","year":"1977","journal-title":"Saishin Igaku"},{"key":"bibr10-106002808301701009","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1001\/jama.1981.03310360040021","volume":"245","author":"Tartas NE","year":"1981","journal-title":"JAMA"},{"key":"bibr11-106002808301701009","volume-title":"A report of cephalothin's leukopenia","year":"1978"},{"key":"bibr12-106002808301701009","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1001\/jama.1973.03220240067027","volume":"224","author":"Silber SJ","year":"1973","journal-title":"JAMA"},{"key":"bibr13-106002808301701009","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1001\/archinte.1979.03630440085029","volume":"139","author":"Homayouni H","year":"1979","journal-title":"Arch Intern Med"},{"key":"bibr14-106002808301701009","first-page":"424","volume":"19","author":"Levin AS","year":"1971","journal-title":"Clin Res"},{"key":"bibr15-106002808301701009","doi-asserted-by":"crossref","first-page":"671","DOI":"10.7326\/0003-4819-83-5-671","volume":"83","author":"Dicato MA","year":"1975","journal-title":"Ann Intern Med"},{"key":"bibr16-106002808301701009","first-page":"403","volume":"33","author":"Hirai K","year":"1979","journal-title":"Kotuh Igaku"},{"key":"bibr17-106002808301701009","doi-asserted-by":"crossref","first-page":"874","DOI":"10.7326\/0003-4819-92-6-874_3","volume":"92","author":"Shansky M","year":"1980","journal-title":"Ann Intern Med"},{"key":"bibr18-106002808301701009","unstructured":"Miller RR, Greenblatt DJ, eds. Drug effects in hospitalized patients. New York: Wiley Biomedical, 1976: 227\u201364."}],"container-title":["Drug Intelligence &amp; Clinical Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/106002808301701009","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/106002808301701009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:01:14Z","timestamp":1777374074000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/106002808301701009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,10]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1983,10]]}},"alternative-id":["10.1177\/106002808301701009"],"URL":"https:\/\/doi.org\/10.1177\/106002808301701009","relation":{},"ISSN":["0012-6578"],"issn-type":[{"value":"0012-6578","type":"print"}],"subject":[],"published":{"date-parts":[[1983,10]]}}}