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Major antiemetic activity was achieved in five patients, two patients had less nausea and vomiting as compared with prior prochlorperazine therapy, and three patients were refractory to droperidol. No dose-response relationship was observed. Sedation occurred in nine patients, and two patients experienced dystonic reactions. Droperidol is a relatively safe and effective antiemetic for patients undergoing chemotherapy with cisplatin.<\/jats:p>","DOI":"10.1177\/106002808501900207","type":"journal-article","created":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T05:08:40Z","timestamp":1512450520000},"page":"118-121","source":"Crossref","is-referenced-by-count":5,"title":["The Antiemetic Activity of Droperidol Administered by Intramuscular Injection during Cisplatin Chemotherapy: A Pilot Study"],"prefix":"10.1177","volume":"19","author":[{"given":"Robert J.","family":"Cersosimo","sequence":"first","affiliation":[{"name":"Clinical Pharmacy, College of Pharmacy and Allied Health Professions, Northeastern University, Boston, MA 02115;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Bromer","sequence":"additional","affiliation":[{"name":"Boston Veterans Administration Medical Center, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Hoffer","sequence":"additional","affiliation":[{"name":"Boston Veterans Administration Medical Center, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Welch","sequence":"additional","affiliation":[{"name":"Boston Veterans Administration Medical Center, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Abrahamson","sequence":"additional","affiliation":[{"name":"Boston Veterans Administration Medical Center, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waun Ki","family":"Hong","sequence":"additional","affiliation":[{"name":"Boston Veterans Administration Medical Center, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,12,5]]},"reference":[{"key":"bibr1-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1016\/S0305-7372(79)80057-2"},{"key":"bibr2-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)59652-4"},{"key":"bibr3-106002808501900207","first-page":"917","volume":"60","author":"YAGODA A.","year":"1976","journal-title":"Cancer Treat Rep"},{"key":"bibr4-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197507242930416"},{"key":"bibr5-106002808501900207","first-page":"167","volume-title":"Treatment of cancer chemotherapy-induced nausea and vomiting.","author":"GRALLA R.J.","year":"1981"},{"key":"bibr6-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198110153051601"},{"key":"bibr7-106002808501900207","volume-title":"Inapsine.","author":"Package insert.","year":"1980"},{"key":"bibr8-106002808501900207","first-page":"361","volume":"53","author":"PATTON C.M.","year":"1974","journal-title":"Anesth Analg (Cleve)"},{"key":"bibr9-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1978.03910060132007"},{"key":"bibr10-106002808501900207","first-page":"674","volume":"56","author":"WINNING T.J.","year":"1977","journal-title":"Anesth Analg (Cleve)"},{"key":"bibr11-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1007\/BF03013781"},{"key":"bibr12-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197907053010116"},{"key":"bibr13-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(80)90063-3"},{"key":"bibr14-106002808501900207","first-page":"381","volume":"21","author":"PALADINE W.","year":"1980","journal-title":"Proc Am Soc Clin Oncol"},{"key":"bibr15-106002808501900207","first-page":"421","volume":"22","author":"WILSON J.","year":"1981","journal-title":"Proc Am Soc Clin Oncol"},{"key":"bibr16-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1177\/106002808201601014"},{"key":"bibr17-106002808501900207","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198107233050420"}],"container-title":["Drug Intelligence &amp; Clinical Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/106002808501900207","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/106002808501900207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:03:15Z","timestamp":1777374195000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/106002808501900207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1985,2]]}},"alternative-id":["10.1177\/106002808501900207"],"URL":"https:\/\/doi.org\/10.1177\/106002808501900207","relation":{},"ISSN":["0012-6578"],"issn-type":[{"value":"0012-6578","type":"print"}],"subject":[],"published":{"date-parts":[[1985,2]]}}}