{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T14:08:27Z","timestamp":1788271707447,"version":"build-2803163510"},"reference-count":33,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[1987,9,1]],"date-time":"1987-09-01T00:00:00Z","timestamp":557452800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug Intelligence &amp; Clinical Pharmacy"],"published-print":{"date-parts":[[1987,9]]},"abstract":"<jats:p>Seventeen nursing home residents with sleeping problems were enrolled in a randomized, double-blind, crossover trial of temazepam 15 mg, diphenhydramine (DPH) 50 mg, and placebo. Each drug was given for five consecutive nights with a 72-hour washout period between drugs. Subjects were assessed three times weekly with tests of psychomotor and cognitive function and four times weekly with observer sleep diaries and morning sleep questionnaires. Three subjects failed to complete the study.<\/jats:p>\n                  <jats:p>By report of the subjects, DPH resulted in shorter sleep latency than did placebo (t = 2.77, p &lt; 0.05). On the fifth night, use of DPH was associated with longer duration of sleep than temazepam (t = 2.88, p &lt; 0.05). No significant difference in tests of neurologic function was noted although, compared with placebo, subjects performed more poorly on seven of eight tests while taking temazepam and five of eight tests while taking DPH. Several instances of daytime hypersomnolence were noted in subjects taking temazepam and DPH, but none in subjects given placebo.<\/jats:p>","DOI":"10.1177\/106002808702100908","type":"journal-article","created":{"date-parts":[[2017,2,13]],"date-time":"2017-02-13T11:52:08Z","timestamp":1486986728000},"page":"716-720","source":"Crossref","is-referenced-by-count":34,"title":["Evaluation of Temazepam and Diphenhydramine as Hypnotics in a Nursing-Home Population"],"prefix":"10.1177","volume":"21","author":[{"given":"Ronald B.","family":"Stewart","sequence":"first","affiliation":[{"name":"Department of Phar-macy Practice, College of Pharmacy, University of Florida, Gainesville, FL 32601."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Meuleman","sequence":"additional","affiliation":[{"name":"Instructor of Medicine;, University of Florida, Gainesville, FL 32602."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C.","family":"Nelson","sequence":"additional","affiliation":[{"name":"Geriatric Medicine Fellow;, University of Florida, Gainesville, FL 32602."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"R. Lee","family":"Clark","sequence":"additional","affiliation":[{"name":"Geriatric Pharmacy Fellow, Geriatric Research, Education, and Clinical Center, Veterans Administration Medical Center; and Department of Medicine, University of Florida, Gainesville, FL 32602."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1987,9,1]]},"reference":[{"key":"bibr1-106002808702100908","volume-title":"Sedative-hypnotic drugs: risks and benefits.","author":"Cooper J.","year":"1977"},{"key":"bibr2-106002808702100908","first-page":"151","volume":"15","author":"Guilleminault C","year":"1977","journal-title":"Confront Psychiatr"},{"key":"bibr3-106002808702100908","first-page":"110","volume":"5","author":"Kripke D","year":"1976","journal-title":"Sleep Res"},{"key":"bibr4-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)31377-3"},{"key":"bibr5-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197302082880602"},{"key":"bibr6-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1977213355"},{"key":"bibr7-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6052.10"},{"key":"bibr8-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1007\/BF00562936"},{"key":"bibr9-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1975.tb00929.x"},{"key":"bibr10-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1976.tb03134.x"},{"key":"bibr11-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1007\/BF00432277"},{"key":"bibr12-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1981.tb03353.x"},{"key":"bibr13-106002808702100908","first-page":"51","volume-title":"Pharmacology of the states of alertness.","author":"Oswald I","year":"1978"},{"key":"bibr14-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1985.tb07155.x"},{"key":"bibr15-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"bibr16-106002808702100908","volume-title":"Symbol digit modalities test.","author":"Smith A.","year":"1973"},{"key":"bibr17-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.48.3.395"},{"key":"bibr18-106002808702100908","volume-title":"Wechsler memory scale.","author":"Wechsler D","year":"1981"},{"key":"bibr19-106002808702100908","volume-title":"Neuropsychological assessment.","author":"Lezak MD.","year":"1983","edition":"2"},{"key":"bibr20-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1080\/01688638208401118"},{"key":"bibr21-106002808702100908","volume-title":"Primer of biostatistics.","author":"Glantz SA.","year":"1981"},{"key":"bibr22-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4943(84)90023-2"},{"key":"bibr23-106002808702100908","first-page":"47","volume":"44","author":"Lader MH.","year":"1983","journal-title":"J Clin Psychiatry"},{"key":"bibr24-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1177\/030006057800600209"},{"key":"bibr25-106002808702100908","first-page":"369","volume":"4","author":"Fillingim JM.","year":"1982","journal-title":"Clin Ther"},{"key":"bibr26-106002808702100908","first-page":"23","volume-title":"Current trends in therapeutics in the elderly.","author":"Cook P.","year":"1980"},{"key":"bibr27-106002808702100908","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-198121050-00001"},{"key":"bibr28-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.280.6214.601"},{"key":"bibr29-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1975172195"},{"key":"bibr30-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1983.tb02730.x"},{"key":"bibr31-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1982.176"},{"key":"bibr32-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198301203080305"},{"key":"bibr33-106002808702100908","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1978234375"}],"container-title":["Drug Intelligence &amp; 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