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This case describes a 26-year-old hemophiliac patient with acquired immunodeficiency syndrome and cryptosporidiosis whose diarrhea improved with continuous intravenous administration of a long-acting somatostatin analog, octreotide. Somatostatin has a variety of inhibitory effects on gastrointestinal hormones as well as a possible nonspecific effect on gastrointestinal mucosal fluid and electrolyte secretion. The somatostatin analog should be considered for patients with secretory diarrhea refractory to other forms of therapy.<\/jats:p>","DOI":"10.1177\/106002808802200206","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T06:08:55Z","timestamp":1496124535000},"page":"134-136","source":"Crossref","is-referenced-by-count":30,"title":["Treatment of Severe Cryptosporidium-Related Diarrhea with Octreotide in a Patient with AIDS"],"prefix":"10.1177","volume":"22","author":[{"given":"Michael D.","family":"Katz","sequence":"first","affiliation":[{"name":"Department of Pharmacy Practice, College of Pharmacy, University of Arizona, Tucson, AZ 85721"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian L.","family":"Erstad","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice, College of Pharmacy, University of Arizona, Tucson, AZ 85721"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathryn","family":"Rose","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, University of Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,5,30]]},"reference":[{"key":"bibr1-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/8.6.1012"},{"key":"bibr2-106002808802200206","volume-title":"Investigator's brochure.","year":"1984"},{"key":"bibr3-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(85)90576-4"},{"key":"bibr4-106002808802200206","first-page":"G221-9","volume":"245","author":"Chew CS","year":"1983","journal-title":"Am J Physiol"},{"key":"bibr5-106002808802200206","doi-asserted-by":"publisher","DOI":"10.3109\/00365527709181727"},{"key":"bibr6-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1210\/endo-99-6-1653"},{"key":"bibr7-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(85)80136-0"},{"key":"bibr8-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1986.01400070103021"},{"key":"bibr9-106002808802200206","doi-asserted-by":"publisher","DOI":"10.3109\/00365527809181925"},{"key":"bibr10-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1159\/000178911"},{"key":"bibr11-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(78)90252-4"},{"key":"bibr12-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-198212000-00008"},{"key":"bibr13-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-48-1-50"},{"key":"bibr14-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198402163100719"},{"key":"bibr15-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(80)90586-7"},{"key":"bibr16-106002808802200206","first-page":"286","volume":"92","author":"Roberts JL","year":"1979","journal-title":"Trans Assoc Am Physicians"},{"key":"bibr17-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(84)90078-7"},{"key":"bibr18-106002808802200206","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1016\/0016-5085(86)90382-3","volume":"90","author":"Roberts WG","year":"1986","journal-title":"Gastroenterology"},{"key":"bibr19-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1007\/BF01297108"},{"key":"bibr20-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198501033120104"},{"key":"bibr21-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198609113151102"},{"key":"bibr22-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.289.6451.1027"},{"key":"bibr23-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800730219"},{"key":"bibr24-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198606263142606"},{"key":"bibr25-106002808802200206","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-105-6-856"},{"key":"bibr26-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1975.03260150029015"},{"key":"bibr27-106002808802200206","doi-asserted-by":"publisher","DOI":"10.2337\/diab.27.3.300"},{"key":"bibr28-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(81)90584-2"},{"key":"bibr29-106002808802200206","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.292.6537.1701"}],"container-title":["Drug Intelligence &amp; 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