{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:05:55Z","timestamp":1777417555147,"version":"3.51.4"},"reference-count":48,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1991,3,1]],"date-time":"1991-03-01T00:00:00Z","timestamp":667785600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DICP"],"published-print":{"date-parts":[[1991,3]]},"abstract":"<jats:p>\n                    We evaluated the effect of phenylpropanolamine hydrochloride (PPA) in 14 young, healthy, normotensive women who concurrently received indomethacin. Subjects received sustained-release (SR) indomethacin 75 mg bid and were randomly assigned to receive double-blind SR PPA 75 mg\/d or placebo for four days. After a six-day washout period, subjects were crossed over to the opposite four-day double-blind treatment. Following an additional six-day washout period, subjects received indomethacin placebo and PPA placebo during a final, single-blind four-day period. Twenty-four-hour blood pressure (BP) monitoring every 30 minutes and a 24-hour urine collection for prostaglandin E\n                    <jats:sub>2<\/jats:sub>\n                    (PGE\n                    <jats:sub>2<\/jats:sub>\n                    ) were performed on the fourth day of each treatment period. Compliance with the medication regimen was confirmed by drug concentrations, pill counts, and urinary PGE\n                    <jats:sub>2<\/jats:sub>\n                    concentrations. Compared with the indomethacin and placebo treatment periods, the combination of indomethacin and PPA had no significant effect on mean systolic or diastolic BP during the 24-hour study period or during any four-hour interval. We conclude that the combination of SR PPA 75 mg\/d and SR indomethacin 150 mg\/d for four days has no adverse effect on BP in normotensive women.\n                  <\/jats:p>","DOI":"10.1177\/106002809102500302","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T15:07:34Z","timestamp":1498748854000},"page":"234-239","source":"Crossref","is-referenced-by-count":3,"title":["The Effect of Phenylpropanolamine on 24-Hour Blood Pressure in Normotensive Subjects Administered Indomethacin"],"prefix":"10.1177","volume":"25","author":[{"given":"James M.","family":"McKenney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Jackson T.","family":"Wight","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gail M.","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert P.","family":"Goodman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1991,3,1]]},"reference":[{"issue":"2","key":"bibr-bibr1-106002809102500302","first-page":"38","volume":"199","year":"1988","journal-title":"Am Drug"},{"key":"bibr-bibr2-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)92360-1"},{"key":"bibr-bibr3-106002809102500302","first-page":"839","volume":"1","year":"1982","journal-title":"Lancet"},{"key":"bibr-bibr4-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5428.193"},{"key":"bibr-bibr5-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196904172801608"},{"key":"bibr-bibr6-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1965.03090170150037"},{"key":"bibr-bibr7-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1966.03100260097036"},{"key":"bibr-bibr8-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1973.03220030058020"},{"key":"bibr-bibr9-106002809102500302","doi-asserted-by":"publisher","DOI":"10.3109\/15563657408988032"},{"key":"bibr-bibr10-106002809102500302","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1978.tb131671.x"},{"key":"bibr-bibr11-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)91791-4"},{"key":"bibr-bibr12-106002809102500302","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1979.tb128964.x"},{"key":"bibr-bibr13-106002809102500302","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1979.tb127123.x"},{"key":"bibr-bibr14-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198303173081111"},{"key":"bibr-bibr15-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198112000-00036"},{"key":"bibr-bibr16-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)92850-2"},{"key":"bibr-bibr17-106002809102500302","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1176\/ajp.137.10.1265","volume":"137","author":"Schaffer CB","year":"1980","journal-title":"Am J Psychiatry"},{"key":"bibr-bibr18-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1981.03310310043020"},{"key":"bibr-bibr19-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.138.3.392a"},{"key":"bibr-bibr20-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1177\/106002808301701008"},{"key":"bibr-bibr21-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.47.1.51"},{"key":"bibr-bibr22-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1016\/0735-6757(87)90097-0"},{"key":"bibr-bibr23-106002809102500302","first-page":"591","volume":"76","author":"Deocampo PD","year":"1979","journal-title":"J Med Soc NJ"},{"key":"bibr-bibr24-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(82)80130-3"},{"key":"bibr-bibr25-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80314-X"},{"key":"bibr-bibr26-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.37.3.399"},{"key":"bibr-bibr27-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90485-3"},{"key":"bibr-bibr28-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.289.6445.591"},{"key":"bibr-bibr29-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1985.03350350103032"},{"key":"bibr-bibr30-106002809102500302","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1987.100"},{"key":"bibr-bibr31-106002809102500302","unstructured":"Gilman AG, Rall TW, Nies AS, Taylor P, eds. 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