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Implementation of the 4-phase instrument review resulted in decreased OHNS surgical instrument set types from 261 to 234 sets, and a decreased number of instruments in these sets from 18 952 to 17 084. The instrument set review resulted in an estimated savings of $35 665 in sterile processing costs for the OHNS department. Instrument review applied to all 10 surgical specialties at the institution would result in an estimated annual savings of $425 378. Through effective leadership, multidisciplinary participation of all key stakeholders, and a systematic approach, this study demonstrates that a hospital-wide quality improvement intervention for instrument set optimization can be successfully performed in a large, multisite tertiary care academic hospital. <\/jats:p>","DOI":"10.1177\/1062860618783261","type":"journal-article","created":{"date-parts":[[2018,6,25]],"date-time":"2018-06-25T07:40:52Z","timestamp":1529912452000},"page":"67-73","update-policy":"http:\/\/dx.doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Implementation and Impact of a Hospital-Wide Instrument Set Review: Early Experiences at a Multisite Tertiary Care Academic Institution"],"prefix":"10.1097","volume":"34","author":[{"given":"Seungwon","family":"Yoon","sequence":"first","affiliation":[{"name":"St. Joseph\u2019s Hospital and Medical Center, Phoenix, AZ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinna C.","family":"Zygourakis","sequence":"additional","affiliation":[{"name":"University of California, San Francisco, CA"},{"name":"Johns Hopkins Hospital, Baltimore, MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Seaman","sequence":"additional","affiliation":[{"name":"University of California, San Francisco, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Zhu","sequence":"additional","affiliation":[{"name":"UCSF Medical Center Administration, San Francisco, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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