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The immunohistochemical evidence of expression of muscle-specific markers supports the rhabdomyomatous nature of this neoplasm, and electron microscopic demonstration of haphazardly arranged myofilaments with prominent Z bands, \u201cjack-straws\u201d in the mitochondria, and the absence of desmosomes is supportive of extracardiac origin of this rhabdomyoma. The possible histogenesis of extracardiac adult rhabdomyoma (EAR) in the anterior-superior mediastinum from the thymic myoid cells is also discussed.<\/jats:p>","DOI":"10.1177\/106689690201000414","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T21:50:28Z","timestamp":1182462628000},"page":"313-318","source":"Crossref","is-referenced-by-count":10,"title":["Mediastinal Rhabdomyoma"],"prefix":"10.1177","volume":"10","author":[{"given":"Jagmohan S.","family":"Sidhu","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, United Health Services Hospitals, Johnson City"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlo M.","family":"Nicolas","sequence":"additional","affiliation":[{"name":"Department of Pathology, SUNY Upstate Medical University, Syracuse, NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, United Health Services Hospitals, Johnson City"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2002,10,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100083092"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31715-1"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(93)90240-H"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0344-0338(88)80105-5"},{"key":"atypb5","first-page":"271","volume":"61","author":"Box JC","year":"1995","journal-title":"Am Surg"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200006000-00011"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197810)42:4<1983::AID-CNCR2820420443>3.0.CO;2-S"},{"key":"atypb8","unstructured":"8. 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