{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:07:27Z","timestamp":1777716447224,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:p>Alveolar rhabdomyosarcoma is an uncommon tumor. It is araremalignancy in adults and rarely occurs in paranasal sinuses in thoseaged older than 50 years. This report describes a locally invasi and destructive alveolar rhabdomyosarcoma arising in the ethmoidsinus of a 57-year-old woman. The small round blue cell tumors are positive for myogenin by immunohistochemistry and have a karyotype of 45, XX, -5, -13, der(16)t(1;1) (q21;q13) by cytogenetic analysis. Fluorescence in situ hybridization demonstrated a complex translocation with break apart of the FKHR region, which supports a diagnosis of alveolar rhabdomyosarcoma. This report characterizes this tumor through microscopic and cyto-genetic analysis and emphasizes the importance of considering rhabdomyosarcoma in the differential diagnosis of small round cell tumors of the head and neck region in the middle-aged adults.<\/jats:p>","DOI":"10.1177\/1066896906290560","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T21:50:28Z","timestamp":1182462628000},"page":"238-242","source":"Crossref","is-referenced-by-count":7,"title":["Alveolar Rhabdomyosarcoma of the Paranasal Sinuses in a 57-Year-Old Woman With 1:16 Translocation"],"prefix":"10.1177","volume":"14","author":[{"given":"Varsha","family":"Manucha","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Maryland Medical Center, Baltimore, Maryland; 20 South Greene Street, Baltimore, MD 21201;."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudy","family":"Castellani","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Maryland Medical Center,Baltimore, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen Chih","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Maryland Medical Center,Baltimore, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,7,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19950915)76:6<1073::AID-CNCR2820760624>3.0.CO;2-L"},{"key":"atypb2","first-page":"47","volume":"11","author":"Hollowood K","year":"1994","journal-title":"Semin Diagn Pathol"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200207000-00014"},{"key":"atypb4","first-page":"3542","volume":"58","author":"Ginsberg JP","year":"1998","journal-title":"Cancer Res"},{"issue":"7","key":"atypb5","first-page":"1711S","volume":"59","author":"Barr FG","year":"1999","journal-title":"Cancer Res"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.03.137"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/0165-4608(95)00267-7"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198204000-00013"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.03.023"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11550"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896906290560","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896906290560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:18:23Z","timestamp":1777457903000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896906290560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["10.1177\/1066896906290560"],"URL":"https:\/\/doi.org\/10.1177\/1066896906290560","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7]]}}}