{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:11:56Z","timestamp":1777716716180,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2008,9,24]],"date-time":"2008-09-24T00:00:00Z","timestamp":1222214400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:p>Cutaneous lymphoid hyperplasia (CLH) is a reactive polyclonal benign lymphoproliferative process predominantly composed of B cells or T cells, either localized or disseminated. The authors report histomorphologic, immunophenotypic, and genotypic findings of 2 cases of B-cell CLH demonstrating progressive transformation of germinal center (PTGC). Histologically, most of the lymphoid follicles were PTGCs with a few hyperplastic germinal centers. PTGC was characterized by enlarged but well-circumscribed follicles without clear demarcation of the germinal center and mantle zone, which contained a predominance of small lymphocytes and variable numbers of centrocytes, centroblasts, and immunoblasts. However, there were no centroblasts and immunoblasts resembling lymphocytic and\/or histiocytic Reed\u2014Sternberg cell variants in nodular lymphocyte\u2014predominant Hodgkin lymphoma (NLPHL) in either lesion. These unusual CLHs should be differentiated from the primary cutaneous marginal zone B-cell lymphoma, primary cutaneous follicular lymphoma, particularly \u201cfloral variant,\u201d or NLPHL. To avoid overdiagnosis and overtreatment, immunophenotypic and genotypic studies are required along with careful morphologic examination.<\/jats:p>","DOI":"10.1177\/1066896908323097","type":"journal-article","created":{"date-parts":[[2008,9,24]],"date-time":"2008-09-24T20:33:59Z","timestamp":1222288439000},"page":"429-432","source":"Crossref","is-referenced-by-count":5,"title":["B-Cell Cutaneous Lymphoid Hyperplasia Representing Progressive Transformation of Germinal Center: A Report of 2 Cases"],"prefix":"10.1177","volume":"18","author":[{"given":"Masaru","family":"Kojima","sequence":"first","affiliation":[{"name":"Department of Pathology and Clinical Laboratories, Gunma Cancer Center Hospital, Ohta,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Sakurai","sequence":"additional","affiliation":[{"name":"Department of Tumor Pathology, Graduate School of Medicine, Gunma University, Maebashi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Saitama Social Insurance Hospital, Saitama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Itoh","sequence":"additional","affiliation":[{"name":"Department of Pathology and Clinical Laboratories, Maebashi Red Cross Hospital, Maebashi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,9,24]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-81092-3_1"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/93.2.219"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199901000-00003"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1982.tb02702.x"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0463.2007.00815.x"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.43.11.888"},{"key":"atypb7","unstructured":"Murphy GF, Schwarting R. Cutaneous lymphomas and leukemias. In: Elder DE, Elenitsas R, Johnson BL Jr, Murphy GF, eds. Levers Histopathology of the Skin. Philadelphia, PA: Lippincott Williams & Wilkins; 2005: 927-978."},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199109000-00001"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-18653-0"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199501000-00002"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199401000-00004"},{"key":"atypb12","unstructured":"Stein H., Delsol G., Pileri S., et al. Nodular lymphocyte predominant Hodgkin lymphoma. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, eds. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001:162-167."},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2003.00167.x"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896908323097","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896908323097","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:19:38Z","timestamp":1777457978000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896908323097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,24]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["10.1177\/1066896908323097"],"URL":"https:\/\/doi.org\/10.1177\/1066896908323097","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,24]]}}}