{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:10:36Z","timestamp":1777716636707,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2009,7,3]],"date-time":"2009-07-03T00:00:00Z","timestamp":1246579200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:p>Small cell carcinoma of the breast is a very rare entity that is histologically indistinguishable from small cell carcinomas of other organs. The presence of an in situ component is the most important feature that indicates the primary nature of the breast tumor. Thyroid transcription factor-1 (TTF-1) is a marker specific to lung and thyroid but is also expressed in small cell carcinoma of pulmonary and extrapulmonary origin. TTF-1 expression in breast small cell carcinoma has been reported only rarely. This reported case is unique because of the characteristic morphological features and immunohistochemical profile. The invasive tumor demonstrated neuroendocrine differentiation morphologically and immunohistochemically, expressed by TTF-1, EGFR, and basal-type cytokeratins. An unequivocal in situ component was identified intimately admixed with the invasive carcinoma. To the authors\u2019 knowledge, this is the first report of breast small cell carcinoma showing the expression of \u201cbasal markers.\u201d<\/jats:p>","DOI":"10.1177\/1066896909340275","type":"journal-article","created":{"date-parts":[[2009,7,3]],"date-time":"2009-07-03T20:25:11Z","timestamp":1246652711000},"page":"368-372","source":"Crossref","is-referenced-by-count":27,"title":["Thyroid Transcription Factor-1 and \u201cBasal Marker\u201d\u2014Expressing Small Cell Carcinoma of the Breast"],"prefix":"10.1177","volume":"17","author":[{"given":"\u00c7a\u011fatay","family":"Er\u015fahin","sequence":"first","affiliation":[{"name":"Department of Pathology, Loyola University Medical Center, Maywood, Illinois, , Department of Pathology, Magee-Women\\s Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudeshna","family":"Bandyopadhyay","sequence":"additional","affiliation":[{"name":"Department of Pathology, Loyola University Medical Center, Maywood, Illinois, Department of Pathology, Wayne State University, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit","family":"Bhargava","sequence":"additional","affiliation":[{"name":"Department of Pathology, Magee-Women\\s Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,7,3]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800678"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1309\/TDP92PQLDE2HLEET"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19841015)54:8<1645::AID-CNCR2820540828>3.0.CO;2-Q"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2002.01336.x"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2000.00890.x"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1038\/35021093"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-0220"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1053\/hupa.2001.25603"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200009000-00006"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-199504000-00008"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19830701)52:1<121::AID-CNCR2820520122>3.0.CO;2-F"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896909340275","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896909340275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:19:18Z","timestamp":1777457958000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896909340275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,3]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["10.1177\/1066896909340275"],"URL":"https:\/\/doi.org\/10.1177\/1066896909340275","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,3]]}}}