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Protein in urine (3.3 g\/d) and Bence-Jones protein of the \u03ba type (2.3 g\/d) were detected. Bone marrow aspiration showed 11.6% monoclonal plasma cells in nucleated cells. A core needle-biopsied and resected left inguinal tumor showed the deposition of eosinophilic amorphous materials positive for Congo red stain and the \u03ba-light chain. He was diagnosed with plasma cell myeloma with AL (amyloid light chain) amyloidosis. Multiple soft-part tumors developed, grew rapidly, and he died 3 months after admission. At autopsy, 3 large amyloidomas were observed in the skeletal muscles, and prominent amyloid deposits were also seen in the diaphragm, intercostal muscle, iliopsoas muscle, and cervical skeletal muscles examined. Massive amyloid materials deposited diffusely in the propria muscularis of the gastrointestinal tract: the tongue to the rectum.<\/jats:p>","DOI":"10.1177\/1066896911410690","type":"journal-article","created":{"date-parts":[[2011,6,3]],"date-time":"2011-06-03T01:51:44Z","timestamp":1307065904000},"page":"83-88","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Bence-Jones Protein\u2013Type Myeloma With Amyloid Myopathy Presenting as Amyloidomas and Extensive Amyloid Deposits in the Muscularis Propria"],"prefix":"10.1177","volume":"20","author":[{"given":"Yoshiyasu","family":"Ikezawa","sequence":"first","affiliation":[{"name":"Mito Saiseikai General Hospital, Mito, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuniyuki","family":"Oka","sequence":"additional","affiliation":[{"name":"Mito Saiseikai General Hospital, Mito, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reizo","family":"Nagayama","sequence":"additional","affiliation":[{"name":"Mito Saiseikai General Hospital, Mito, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Okubo","sequence":"additional","affiliation":[{"name":"Mito Saiseikai General Hospital, Mito, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Yonekawa","sequence":"additional","affiliation":[{"name":"Mito Saiseikai General Hospital, Mito, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Futoshi","family":"Hirai","sequence":"additional","affiliation":[{"name":"Mito Saiseikai General Hospital, Mito, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itaru","family":"Ebihara","sequence":"additional","affiliation":[{"name":"Mito Saiseikai General Hospital, Mito, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoyoshi","family":"Mori","sequence":"additional","affiliation":[{"name":"Nakatsugawa City Hospital, Nakatsugawa, Gifu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,6,1]]},"reference":[{"key":"bibr1-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1080\/13506120701460923"},{"key":"bibr2-1066896911410690","first-page":"200","volume-title":"WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues","author":"McKenna RW","year":"2008","edition":"4"},{"key":"bibr3-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(98)90061-2"},{"key":"bibr4-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1007\/BF00695574"},{"key":"bibr5-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(88)90158-X"},{"key":"bibr6-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1080\/03009740510026355"},{"key":"bibr7-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-09-2707"},{"key":"bibr8-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1159\/000168987"},{"key":"bibr9-1066896911410690","first-page":"394","volume":"53","author":"Kanai H","year":"2000","journal-title":"Clin Nephrol"},{"key":"bibr10-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1136\/gut.34.10.1412"},{"key":"bibr11-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1136\/gut.10.2.98"},{"key":"bibr12-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000981"},{"key":"bibr13-1066896911410690","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.3.714"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896911410690","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1066896911410690","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896911410690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:18:20Z","timestamp":1777457900000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896911410690"}},"subtitle":["A Rapidly Fatal Autopsy Case"],"short-title":[],"issued":{"date-parts":[[2011,6,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.1177\/1066896911410690"],"URL":"https:\/\/doi.org\/10.1177\/1066896911410690","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,1]]}}}