{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:07:23Z","timestamp":1777716443377,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,9,12]],"date-time":"2011-09-12T00:00:00Z","timestamp":1315785600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p>IgG4-related sclerosing disease (IRSD) is a steroid-responsive fibroinflammatory disorder characterized by increased IgG4+ cells. Nodal involvement usually lacks the dense sclerosis seen in extranodal sites, with histologic patterns overlapping with other reactive processes. Twenty-six lymph nodes showing IRSD-related histologic patterns were evaluated for IgG and IgG4 positive cells by immunohistochemistry and correlated with the clinical features. Cases included 7 Castleman disease\u2013like cases (type I pattern), 10 follicular hyperplasia (type II), and 9 plasmacytosis (type III). The mean numbers of IgG4+ cells per high-power field (HPF) were 4.8 (I), 8.4 (II), and 26.6(III), and the mean IgG4\/IgG ratios were 0.05 (I), 0.04 (II), and 0.08 (III). Using &gt;50 IgG4+cells\/HPF and IgG4\/IgG ratio of &gt;0.4 for absolute and relative increases, only 1 case fulfilled both criteria for increased IgG4+ cells, a patient with Hashimoto\u2019s thyroiditis without clinical evidence of IRSD. The results suggest that increased IgG4+ cells may rarely be seen in non-IRSD lymph nodes.<\/jats:p>","DOI":"10.1177\/1066896911420562","type":"journal-article","created":{"date-parts":[[2011,9,13]],"date-time":"2011-09-13T02:21:53Z","timestamp":1315880513000},"page":"47-53","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Increased Numbers of IgG4-Positive Plasma Cells May Rarely Be Seen in Lymph Nodes of Patients Without IgG4-Related Sclerosing Disease"],"prefix":"10.1177","volume":"20","author":[{"given":"Marian A.","family":"Rollins-Raval","sequence":"first","affiliation":[{"name":"University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond E.","family":"Felgar","sequence":"additional","affiliation":[{"name":"University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa M.","family":"Krasinskas","sequence":"additional","affiliation":[{"name":"University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine G.","family":"Roth","sequence":"additional","affiliation":[{"name":"University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,9,12]]},"reference":[{"key":"bibr1-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0b013e3181ee63ce"},{"key":"bibr2-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181abdfc2"},{"key":"bibr3-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181998cbe"},{"key":"bibr4-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e328341347b"},{"key":"bibr5-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181c811ad"},{"key":"bibr6-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20215"},{"key":"bibr7-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318059b87c"},{"key":"bibr8-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103083441005"},{"key":"bibr9-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(05)00561-4"},{"key":"bibr10-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318157c068"},{"key":"bibr11-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2009.17"},{"key":"bibr12-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-010-0721-7"},{"key":"bibr13-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2010.02524.x"},{"key":"bibr14-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpa.0000167000.11889.3a"},{"key":"bibr15-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-006-1868-0"},{"key":"bibr16-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.05.017"},{"key":"bibr17-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213331.09864.2c"},{"key":"bibr18-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-005-2703-9"},{"key":"bibr19-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2009.02419.x"},{"key":"bibr20-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-1794"},{"key":"bibr21-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181ac43b6"},{"key":"bibr22-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2010.082958"},{"key":"bibr23-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2008.01222.x"},{"key":"bibr24-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2010.03519.x"},{"key":"bibr25-1066896911420562","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.226"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896911420562","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1066896911420562","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896911420562","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:18:22Z","timestamp":1777457902000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896911420562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,12]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.1177\/1066896911420562"],"URL":"https:\/\/doi.org\/10.1177\/1066896911420562","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,12]]}}}