{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:10:53Z","timestamp":1787019053692,"version":"build-2736575974"},"reference-count":21,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T00:00:00Z","timestamp":1469664000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Basosquamous carcinoma is a rare cutaneous tumor considered by some authors as an aggressive type of basal cell carcinoma having a propensity for local recurrence and a potential risk for regional and distant metastatic spread. Herein we present 2 cases of basosquamous carcinoma of head and neck region, with metastatic spread to parotid gland (case 1) and to cervical nodes (case 2). Both patients had recurrence 2 years after initial treatment of the primary lesion (first patient: surgery; second patient: radiotherapy) and at the same time developed regional metastases. We conclude that basosquamous carcinoma must be considered as an aggressive variant of basal cell carcinoma having a great propensity to metastasize even at an early tumor stage. The clinical features, the morphologic aspects, and the treatment of this rare entity are discussed in this article.<\/jats:p>","DOI":"10.1177\/1066896916651493","type":"journal-article","created":{"date-parts":[[2016,5,27]],"date-time":"2016-05-27T21:09:28Z","timestamp":1464383368000},"page":"726-732","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Metastatic Basosquamous Carcinoma"],"prefix":"10.1177","volume":"24","author":[{"given":"Tommaso","family":"Bucci","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Surgery, University of Verona, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Santoro","sequence":"additional","affiliation":[{"name":"Department of Laboratory and Services, Institute of Histopathology and Diagnostic Cytopathology, Fondazione di Ricerca e Cura \u201cGiovanni Paolo II\u201d-UCSC, Campobasso, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Pannone","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Institute of Pathological Anatomy, University of Foggia, Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxilofacial Surgery, Joan XXIII Hospital, Tarragona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Fior","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery, University of Verona, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Francesco","family":"Nocini","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery, University of Verona, Verona, 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