{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T11:47:24Z","timestamp":1784634444681,"version":"3.55.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T00:00:00Z","timestamp":1508976000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Background: Composite small lymphocytic lymphoma\/chronic lymphocytic leukemia (SLL\/CLL) and follicular lymphoma (FL) is extremely rare, and only 13 cases have been reported previously. Methods: We identified 6 cases of composite SLL\/CLL and FL in our database and studied their clinical, histologic, immunophenotypic, and cytogenetic features. A literature review of the existing cases was also conducted. Results: The patients included 4 males and 2 females, with a median age of 72 years. Four patients presented with lymphadenopathy and 2 with extranodal diseases. Lymphocytosis was seen in 2 cases. Serum lactate dehydrogenase levels were within normal range in all but one case. There were 2 histologic patterns: SLL\/CLL predominant pattern (type I) and FL predominant or mixed pattern (type II). The type I pattern was exclusively associated with in situ follicular neoplasia (ISFN). The SLL\/CLL showed typical morphology and immunophenotype in all the cases. The FL component included low grade (n = 3), ISFN (n = 2), and primary cutaneous FL (n = 1). Four cases had staging bone marrow biopsies including 3 cases with involvement by SLL\/CLL and 1 case with involvement by SLL\/CLL and FL. Four patients received treatments, one was under clinical surveillance, and one had no available information. All patients were alive after a median follow-up of 22 months. Conclusions: This is the largest case serial of composite SLL\/CLL and FL. The CL affects elderly individuals, presents with advanced clinical stage, and appears to have a relatively indolent clinical course.<\/jats:p>","DOI":"10.1177\/1066896917737161","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T04:57:09Z","timestamp":1508993829000},"page":"135-144","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Composite Small Lymphocytic Lymphoma\/Chronic Lymphocytic Leukemia and Follicular Lymphoma: A Clinicopathological Study of Six Cases"],"prefix":"10.1177","volume":"26","author":[{"given":"Fatima Zahra","family":"Jelloul","sequence":"first","affiliation":[{"name":"Hofstra Northwell School of Medicine, Lake Success, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang Hua","family":"Chen","sequence":"additional","affiliation":[{"name":"Hofstra Northwell School of Medicine, Lake Success, NY, 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