{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:15:04Z","timestamp":1792818904150,"version":"4.5.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T00:00:00Z","timestamp":1531958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>Background. In this study, we retrospectively evaluated cases of patients who had undergone appendectomy in our hospital and aimed to present the efficiency of diagnostic tests and demographic data of cases. Pathological reports were analyzed for the following parameters: age, gender, and pathological diagnosis. In addition, the demographic and clinicopathologic characteristics of patients with unusual histopathologic findings were evaluated in detail, and reanalysis of archived resected appendix specimens was carried out. Methods. Files of 2047 patients (1329 males, 718 females, sex ratio: 1.85, age range: 1-87 years, mean age: 26, 50 years), who had been operated with a diagnosis of acute appendicitis in the emergency department of Bezmialem Vak\u0131f University Medical Faculty from November 2011 to June 2014, were retrospectively evaluated. Results. Cases were separated into 2 groups. Cases with histopathologic examination reported as acute appendicitis constituted group 1 (n = 2013, 98.34%), and cases with pathologic findings other than acute appendicitis constituted group 2 (n = 34, 1.66%). The second group consisted of 8 low-grade mucinous neoplasms, 7 mucoceles, 6 carcinoid, 5 granulomatous inflammation, 4 intraluminal Enterobius vermicularis, 1 endometriosis externa, 1 adenocarcinoma infiltrated to serosa, 1 mesenteric cyst, and 1 low-grade adenocarcinoma formed in mucinous cystic neoplasm background. Conclusion. Acute appendicitis is the most common emergency surgical condition. Although most of the resected appendectomy specimens showed typical histopathologic findings, some (1.66%) showed unusual histopathologic findings. Even if the macroscopic appearance of the specimen is normal or acute appendicitis, we suggest routine histopathological examination.<\/jats:p>","DOI":"10.1177\/1066896918784650","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T05:03:36Z","timestamp":1531976616000},"page":"142-146","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":37,"title":["Unusual Histopathological Findings in Appendectomy Specimens: A Retrospective Analysis of 2047 Cases"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7392-6099","authenticated-orcid":false,"given":"Nurcan","family":"Unver","sequence":"first","affiliation":[{"name":"Bezmialem Vakif University, Faculty of Medicine, Department of Pathology, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganime","family":"Coban","sequence":"additional","affiliation":[{"name":"Bezmialem Vakif University, Faculty of Medicine, Department of Pathology, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek Sema","family":"Ar\u0131c\u0131","sequence":"additional","affiliation":[{"name":"Bezmialem Vakif University, Faculty of Medicine, Department of Pathology, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nur","family":"Buyukp\u0131narbas\u0131l\u0131","sequence":"additional","affiliation":[{"name":"Bezmialem Vakif University, Faculty of Medicine, Department of Pathology, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuhal","family":"Gucin","sequence":"additional","affiliation":[{"name":"Bezmialem Vakif University, Faculty of Medicine, Department of Pathology, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma \u00dcmit","family":"Malya","sequence":"additional","affiliation":[{"name":"Bezmialem Vakif University, Faculty of Medicine, Department of General Surgery, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oyku Izel","family":"Onaran","sequence":"additional","affiliation":[{"name":"Kesan Comminty Health Center, Edirne, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u0131vanc","family":"Topalan","sequence":"additional","affiliation":[{"name":"Bezmialem Vakif University, Faculty of Medicine, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,7,19]]},"reference":[{"key":"bibr1-1066896918784650","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i15.1961"},{"key":"bibr2-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-014-1934-7"},{"key":"bibr3-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2010.02457.x"},{"key":"bibr4-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1308\/003588413X13511609954851"},{"key":"bibr5-1066896918784650","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2017.3.18061"},{"key":"bibr6-1066896918784650","doi-asserted-by":"publisher","DOI":"10.5812\/ircmj.12931"},{"key":"bibr7-1066896918784650","unstructured":"Bosman FT, Carnerio F, Hruban RH, Theise ND. WHO Classification of Tumours of the Digestive System. 4th ed. Lyon, France: IARC Press; 2010:126."},{"key":"bibr8-1066896918784650","first-page":"601","volume":"38","author":"Moris D","year":"2018","journal-title":"Anticancer Res"},{"key":"bibr9-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000535"},{"key":"bibr10-1066896918784650","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i25.4015"},{"key":"bibr11-1066896918784650","volume-title":"Schwartz\u2019s Principles of Surgery","volume":"2010","author":"Brunicardi F","year":"1075","edition":"9"},{"key":"bibr12-1066896918784650","unstructured":"Cameron JL, Cameron AM. Current Surgical Therapy. 10th ed. Philadelphia, PA: Mosby; 2011:219."},{"key":"bibr13-1066896918784650","unstructured":"Longo DL, Fauci AS, Kasper DL, et al. Harrison\u2019s Principles of Internal Medicine. 18th ed. New York, NY: McGraw-Hill; 2012:516."},{"key":"bibr14-1066896918784650","unstructured":"Rosai J. Rosai and Ackerman\u2019s Surgical Pathology. 10th ed. Philadelphia, PA: Mosby; 2011:714."},{"key":"bibr15-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2008.03.040"},{"key":"bibr16-1066896918784650","doi-asserted-by":"publisher","DOI":"10.9738\/INTSURG-D-13-00098.1"},{"key":"bibr17-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1530\/ERC-15-0310"},{"key":"bibr18-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1177\/1066896909349246"},{"key":"bibr19-1066896918784650","doi-asserted-by":"publisher","DOI":"10.5152\/tpd.2012.09"},{"key":"bibr20-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2010.06.007"},{"key":"bibr21-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1080\/00365520802624227"},{"key":"bibr22-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-005-1408-5"},{"key":"bibr23-1066896918784650","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.59380"},{"key":"bibr24-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1177\/1066896909332728"},{"key":"bibr25-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-007-0304-0"},{"key":"bibr26-1066896918784650","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.1472"},{"key":"bibr27-1066896918784650","first-page":"629","volume":"67","author":"Fu TY","year":"2004","journal-title":"J Chin Med Assoc"},{"key":"bibr28-1066896918784650","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-008-0922-y"},{"key":"bibr29-1066896918784650","first-page":"1610","volume":"123","author":"Astroza G","year":"2010","journal-title":"Chin Med J (Engl)"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896918784650","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1066896918784650","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896918784650","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:22:28Z","timestamp":1777458148000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896918784650"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,19]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1177\/1066896918784650"],"URL":"https:\/\/doi.org\/10.1177\/1066896918784650","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,19]]}}}