{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:15:22Z","timestamp":1777716922758,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T00:00:00Z","timestamp":1556582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>We present 6 cases with multifocal appendiceal neuroendocrine tumors, including their clinical and histopathological findings. To our knowledge, this is the first description of a multifocal pattern of a neuroendocrine neoplasm arising in the appendix. All patients presented in a setting requiring an acute appendectomy. The number of tumors ranged from 2 to 5. Histopathological examination revealed WHO (World Health Organization) grade 1 tumor in 3 patients and WHO grade 2 in the other 3 patients. The median duration of follow-up in these patients was 70 months (range = 6-192 months). No metastatic disease was observed. According to these findings, a multifocal pattern of neuroendocrine neoplasms along the appendix seems not to be a predictor for local advanced or metastatic disease.<\/jats:p>","DOI":"10.1177\/1066896919845048","type":"journal-article","created":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T02:42:30Z","timestamp":1556678550000},"page":"613-618","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A Multifocal Pattern of Neuroendocrine Neoplasms Along the Appendix: A Series of Six Cases"],"prefix":"10.1177","volume":"27","author":[{"given":"Hema","family":"Mahajan","sequence":"first","affiliation":[{"name":"Department of Tissue Pathology, NSW Pathology ICPMR, Westmead Hospital, Westmead, NSW; Western Sydney University, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6396-3977","authenticated-orcid":false,"given":"Martijn Pieter","family":"Gosselink","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Westmead Hospital, The University of Sydney Westmead Clinical School, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelina M.","family":"Di Re","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Westmead Hospital, The University of Sydney Westmead Clinical School, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Larcos","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine & Ultrasound, Westmead Hospital, The University of Sydney Westmead Clinical School, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chow Heok","family":"P\u2019ng","sequence":"additional","affiliation":[{"name":"Department of Tissue Pathology, NSW Pathology ICPMR, Westmead Hospital, Westmead, NSW; Western Sydney University, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grahame","family":"Ctercteko","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Westmead Hospital, The University of Sydney Westmead Clinical School, Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,4,30]]},"reference":[{"key":"bibr1-1066896919845048","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.00422.x"},{"key":"bibr2-1066896919845048","doi-asserted-by":"publisher","DOI":"10.1007\/BF02236899"},{"key":"bibr3-1066896919845048","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050937"},{"key":"bibr4-1066896919845048","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002736"},{"key":"bibr5-1066896919845048","volume-title":"The Second Australian Atlas of Healthcare Variation","author":"Australian Commission on Safety and Quality in Health Care; Australian Institute of Health and Welfare","year":"2017"},{"key":"bibr6-1066896919845048","volume-title":"New South Wales Admitted Patient Report 2012","author":"Population and Public Health Division","year":"2012"},{"key":"bibr7-1066896919845048","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v2.i4.192"},{"key":"bibr8-1066896919845048","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198712313172704"},{"key":"bibr9-1066896919845048","doi-asserted-by":"publisher","DOI":"10.3348\/jksr.2014.70.5.355"},{"key":"bibr10-1066896919845048","doi-asserted-by":"publisher","DOI":"10.1016\/S1479-666X(07)80065-5"},{"key":"bibr11-1066896919845048","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1995.tb00327.x"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896919845048","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1066896919845048","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896919845048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:20:40Z","timestamp":1777458040000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896919845048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,30]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1177\/1066896919845048"],"URL":"https:\/\/doi.org\/10.1177\/1066896919845048","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,30]]}}}