{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:16:40Z","timestamp":1777717000215,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:00:00Z","timestamp":1571875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:p>Background. In this single-institution study, we applied the current (eighth edition) American Joint Committee on Cancer pathologic staging criteria to 64 low-grade mucinous neoplasms of the appendix (LAMNs), examined their histopathologic features, and studied the patients\u2019 clinical outcomes. Design. Sixty-four LAMNs, with a median follow-up of 52 months, were reviewed. Results. The distribution of pathologic stages was pTis (n = 39), pT3 (n = 1), pT4a (n = 5), pT4aM1a (n = 8), and pT4aM1b (n = 11). Recurrence was observed in only 2 patients (both with pT4aM1b disease), one of whom died of disease. All remaining patients were disease-free after a median clinical follow-up of 60 months. Conclusions. Our study confirms that pTis LAMNs have an excellent prognosis and suggests that pT4a and pT4aM1a LAMNs may also have a low risk of developing progressive disease.<\/jats:p>","DOI":"10.1177\/1066896919883679","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T10:25:41Z","timestamp":1571912741000},"page":"252-258","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Low-Grade Appendiceal Mucinous Neoplasms: A Single Institution Experience of 64 Cases With Clinical Follow-up and Correlation With the Current (Eighth Edition) AJCC Staging"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0396-2232","authenticated-orcid":false,"given":"Mary","family":"Wong","sequence":"first","affiliation":[{"name":"Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad","family":"Barrows","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Gangi","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey","family":"Kim","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard B.","family":"Mertens","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepti","family":"Dhall","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,10,24]]},"reference":[{"key":"bibr1-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200308000-00006"},{"key":"bibr2-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181af6067"},{"key":"bibr3-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1097\/01.pap.0000194625.05137.51"},{"key":"bibr4-1066896919883679","first-page":"71","volume":"134","author":"Pai RK","year":"2007","journal-title":"Cancer Treat Res"},{"key":"bibr5-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199512000-00006"},{"key":"bibr6-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000535"},{"key":"bibr7-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19950201)75:3<757::AID-CNCR2820750303>3.0.CO;2-F"},{"key":"bibr8-1066896919883679","volume-title":"WHO Classification of Tumours of the Digestive System","author":"Misdragi J","year":"2019","edition":"5"},{"key":"bibr9-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31817ec31e"},{"key":"bibr10-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-40618-3"},{"key":"bibr11-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-017-6310-8"},{"key":"bibr12-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2017.09.005"},{"key":"bibr13-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197312)32:6<1525::AID-CNCR2820320632>3.0.CO;2-C"},{"key":"bibr14-1066896919883679","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-018-7003-7"},{"key":"bibr15-1066896919883679","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2014-0246-OA"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896919883679","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1066896919883679","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896919883679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:20:55Z","timestamp":1777458055000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896919883679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,24]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1177\/1066896919883679"],"URL":"https:\/\/doi.org\/10.1177\/1066896919883679","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,24]]}}}