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In this article, we report a case of low-grade breast mucoepidermoid carcinoma of a 60-year-old female patient. Histologic and immunohistochemical patterns were demonstrated. Fluorescence in situ hybridization test was also conducted to identify MAML2 rearrangement in this case, indicating a similar molecular abnormality as mucoepidermoid carcinoma in the salivary gland. Five-year follow-up of the patient showed no local recurrence or distant metastasis of the carcinoma, indicating the indolent behavior of low-grade breast mucoepidermoid carcinoma. Besides, a 40-year literature review from 1979 to 2019 was also performed to better characterize the prognosis and molecular abnormalities of the lesion.<\/jats:p>","DOI":"10.1177\/1066896920916779","type":"journal-article","created":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T04:38:45Z","timestamp":1588567125000},"page":"787-792","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["Mucoepidermoid Carcinoma of the Breast With\n                    <i>MAML2<\/i>\n                    Rearrangement: A Case Report and Literature Review"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2054-5986","authenticated-orcid":false,"given":"Mingfei","family":"Yan","sequence":"first","affiliation":[{"name":"University Hospitals Cleveland Medical Center, Cleveland, OH, USA"},{"name":"Case Western Reserve University, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Gilmore","sequence":"additional","affiliation":[{"name":"University Hospitals Cleveland Medical Center, Cleveland, OH, USA"},{"name":"Case Western Reserve University, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparna","family":"Harbhajanka","sequence":"additional","affiliation":[{"name":"University Hospitals Cleveland Medical Center, Cleveland, OH, USA"},{"name":"Case Western Reserve University, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,5,4]]},"reference":[{"key":"bibr1-1066896920916779","first-page":"196","volume":"103","author":"Patchefsky AS","year":"1979","journal-title":"Arch Pathol Lab Med"},{"key":"bibr2-1066896920916779","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-1578(10)60511-9"},{"key":"bibr3-1066896920916779","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2009.12.007"},{"key":"bibr4-1066896920916779","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198301000-00002"},{"key":"bibr5-1066896920916779","volume-title":"WHO Classification of Tumours. 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