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COST appears to have a sporadic presentation, affecting both sexes and patients of variable ethnicity and age group and predominantly occurring on the bulbar conjunctiva as a slow-growing asymptomatic or slightly tender mass-like lesion. Histopathologically, COST is characterized by singly dispersed spindle to round cells, often with some degree of degenerative nuclear atypia, within a myxomatous to collagenous stroma. Lesional cells are characteristically positive for CD34 and vimentin, negative for S100, SOX10 and STAT6 and show a normal pattern of staining with RB1 by immunohistochemistry. The reported cases to date have shown an indolent biological behavior, reliably treated by a complete surgical excision.<\/jats:p>","DOI":"10.1177\/1066896920945783","type":"journal-article","created":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T05:47:26Z","timestamp":1596001646000},"page":"337-342","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Conjunctival Stromal Tumor: Report of 2 New Cases and Review of the Literature"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1409-0521","authenticated-orcid":false,"given":"Jonathan","family":"Lam","sequence":"first","affiliation":[{"name":"University of Western Australia, Perth, Western Australia, Australia"},{"name":"Fremantle Hospital, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Ang","sequence":"additional","affiliation":[{"name":"University of Western Australia, Perth, Western Australia, Australia"},{"name":"Royal Perth Hospital, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tersia","family":"Vermeulen","sequence":"additional","affiliation":[{"name":"PathWest Laboratory Medicine, QEII Medical Centre, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nima Mesbah","family":"Ardakani","sequence":"additional","affiliation":[{"name":"University of Western Australia, Perth, Western Australia, Australia"},{"name":"PathWest Laboratory Medicine, QEII Medical Centre, Perth, Western Australia, Australia"},{"name":"Murdoch University, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,7,29]]},"reference":[{"key":"bibr1-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2018-312747"},{"key":"bibr2-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.09.024"},{"key":"bibr3-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.10.002"},{"key":"bibr4-1066896920945783","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2018.0059"},{"key":"bibr5-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2015.11.027"},{"key":"bibr6-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-230348"},{"key":"bibr7-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1111\/his.13274"},{"key":"bibr8-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1172\/JCI10841"},{"key":"bibr9-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-15-0209"},{"key":"bibr10-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1016\/S1085-5629(05)80003-3"},{"key":"bibr11-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-016-0233-1"},{"key":"bibr12-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1159\/000112632"},{"key":"bibr13-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.124.5.735"},{"key":"bibr14-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2013.164"},{"key":"bibr15-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000189"},{"key":"bibr16-1066896920945783","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2019.02.005"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896920945783","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1066896920945783","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896920945783","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:21:28Z","timestamp":1777458088000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896920945783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,29]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1177\/1066896920945783"],"URL":"https:\/\/doi.org\/10.1177\/1066896920945783","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,29]]}}}