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It may be associated with poorer clinical outcome and could pose a diagnostic challenge, particularly if it occurs in older patients or as a metastatic lesion. We present a case of Ewing sarcoma in the metatarsal of an 11-year-old boy that manifested adamantinoma-like morphology after neoadjuvant chemotherapy. Chemotherapy has been reported to induce neuronal maturation and rhabdoid morphology in cases of Ewing sarcoma, but no reports of treatment-induced squamous differentiation with P40\/P63 expression have been demonstrated. This is also the first documented case treated with a pedicled osteocutaneous fibular transfer in a metatarsal malignancy, which is usually treated by either ray or below-knee amputation.<\/jats:p>","DOI":"10.1177\/10668969211001449","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T08:00:19Z","timestamp":1615449619000},"page":"798-803","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Adamantinoma-like Variant of Ewing Sarcoma in the Metatarsal Bone After Chemotherapy: Report of a Case Successfully Treated with Pedicled Osteocutaneous Fibular Transfer"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1170-6378","authenticated-orcid":false,"given":"Yolandi A.","family":"Marais","sequence":"first","affiliation":[{"name":"National Health Laboratory Service, Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron K.","family":"Saini","sequence":"additional","affiliation":[{"name":"Division of Orthopaedic Surgery, Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nando","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Division of Orthopaedic Surgery, Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kershinee","family":"Reddy","sequence":"additional","affiliation":[{"name":"Paediatric Oncology Unit, Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Z\u00fchlke","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelmarie","family":"Rossouw","sequence":"additional","affiliation":[{"name":"Division of Radiodiagnosis, Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan D.","family":"Zaharie","sequence":"additional","affiliation":[{"name":"National Health Laboratory Service, Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawel T.","family":"Schubert","sequence":"additional","affiliation":[{"name":"National Health Laboratory Service, Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,3,11]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2014.01.002"},{"key":"e_1_3_2_3_2","volume-title":"Soft Tissue and Bone Tumours","author":"Antonescu C","year":"2020","unstructured":"Antonescu C. 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