{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:21:01Z","timestamp":1777717261056,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:p>A small cell-like change in prostate has been described in high-grade prostatic intraepithelial neoplasia (PIN), intraductal prostatic adenocarcinoma, and invasive prostate cancer. It occurs when these processes have a cribriform architecture. To date, small cell-like change has not been described in benign glands. Herein, I describe such a change in cribriform central zone histology from a radical prostatectomy with a spatially remote treatment na\u00efve Grade Group 3 prostate cancer. The cancer did not have cribriform morphology or intraductal prostatic adenocarcinoma. The small cell-like change was positive for racemase in PIN-4 cocktail and no nuclei were highlighted by Ki-67. This is the first report of a small cell-like change in benign prostate tissue. Although rare, such finding in cribriform architecture of central zone histology can potentially be misinterpreted as a neoplastic process.<\/jats:p>","DOI":"10.1177\/10668969211003966","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T12:37:29Z","timestamp":1615984649000},"page":"635-637","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Small Cell-like Change in Central Zone Histology\u2014A New Observation Mimicking Cribriform Intraductal Prostatic Adenocarcinoma"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5731-1748","authenticated-orcid":false,"given":"Oleksandr N.","family":"Kryvenko","sequence":"first","affiliation":[{"name":"University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"bibr1-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800702"},{"key":"bibr2-10668969211003966","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2015-0487-SA"},{"key":"bibr3-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPZ7WBU9YXSJPE"},{"key":"bibr4-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-015-1809-5"},{"key":"bibr5-10668969211003966","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2012-0128-OA"},{"key":"bibr6-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2016.07.012"},{"key":"bibr7-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1111\/his.13767"},{"key":"bibr8-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1111\/his.13747"},{"key":"bibr9-10668969211003966","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2020-0015-RA"},{"key":"bibr10-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001497"},{"key":"bibr11-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-016-2033-7"},{"key":"bibr12-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2012.06.008"},{"key":"bibr13-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800050"},{"key":"bibr14-10668969211003966","doi-asserted-by":"publisher","DOI":"10.5858\/2007-131-1257-PINRA"},{"key":"bibr15-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.53.9.655"},{"key":"bibr16-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199710000-00013"},{"key":"bibr17-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2014.21"},{"key":"bibr18-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318058a96b"},{"key":"bibr19-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/49.3.347"},{"key":"bibr20-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198808000-00003"},{"key":"bibr21-10668969211003966","doi-asserted-by":"publisher","DOI":"10.1053\/hupa.2002.124032"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969211003966","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10668969211003966","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969211003966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:21:41Z","timestamp":1777458101000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10668969211003966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,17]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1177\/10668969211003966"],"URL":"https:\/\/doi.org\/10.1177\/10668969211003966","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,17]]}}}