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The neoplastic nature of the lesion has been supported by a recurrent CSF1 gene rearrangement in a small subset of lesional cells, of which the most common fusion partner is COL6A3. Herein, we report a case of intramuscular localized tenosynovial giant cell tumor harboring a novel CSF1-CD96 fusion transcript, thus expanding the molecular profile of this tumor.<\/jats:p>","DOI":"10.1177\/10668969211049833","type":"journal-article","created":{"date-parts":[[2021,10,16]],"date-time":"2021-10-16T05:22:23Z","timestamp":1634361743000},"page":"335-338","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Intramuscular Tenosynovial Giant Cell Tumor Harboring a Novel\n                    <i>CSF1-CD96<\/i>\n                    Fusion Transcript"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3695-8192","authenticated-orcid":false,"given":"Haider","family":"Mejbel","sequence":"first","affiliation":[{"name":"University of Alabama at Birmingham, Birmingham, AL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gene P.","family":"Siegal","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham, Birmingham, AL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4417-593X","authenticated-orcid":false,"given":"Shi","family":"Wei","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham, Birmingham, AL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,10,16]]},"reference":[{"key":"bibr1-10668969211049833","first-page":"133","volume-title":"WHO Classification of Tumors: Soft Tissue and Bone","author":"de Saint Aubain Somerhausen N","year":"2020","edition":"5"},{"key":"bibr2-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-018-0129-0"},{"key":"bibr3-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200004000-00002"},{"key":"bibr4-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-006-0112-6"},{"key":"bibr5-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-014-1854-1"},{"key":"bibr6-10668969211049833","doi-asserted-by":"publisher","DOI":"10.4132\/jptm.2015.11.15"},{"key":"bibr7-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.20501"},{"key":"bibr8-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31802b86f8"},{"key":"bibr9-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.32421"},{"key":"bibr10-10668969211049833","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2014.2326"},{"key":"bibr11-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1177\/1066896910381899"},{"key":"bibr12-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-002-0640-y"},{"key":"bibr13-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.2870040312"},{"key":"bibr14-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507321103"},{"key":"bibr15-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00132-1"},{"key":"bibr16-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411366"},{"key":"bibr17-10668969211049833","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.7.3994"},{"key":"bibr18-10668969211049833","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-15-0944"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969211049833","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10668969211049833","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969211049833","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:21:54Z","timestamp":1777458114000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10668969211049833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,16]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1177\/10668969211049833"],"URL":"https:\/\/doi.org\/10.1177\/10668969211049833","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,16]]}}}