{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:23:57Z","timestamp":1777717437971,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T00:00:00Z","timestamp":1613952000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T00:00:00Z","timestamp":1613952000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>Two sporadic cases of eosinophilic solid and cystic renal cell carcinoma (ESC RCC), at our institution, are presented in this study to contribute to the growing literature on this novel renal neoplasm. The first patient was a 38-year-old female with two synchronous renal masses measuring 3.5 and 1.9\u2005cm on preoperative imaging. The second patient was a 44-year-old female with an incidental renal mass measuring 4\u2005cm. Both patients underwent uncomplicated radical nephrectomies. The 1.9\u2005cm mass in the first patient was consistent with clear cell RCC. The dominant mass in the first patient and the tumor in the second patient had microscopic and macroscopic findings in keeping with ESC RCC including a tan appearance, abundant eosinophilic cytoplasm, and CK20+ and CK7\u2212 staining. Both patients had an uncomplicated course following surgery with no evidence of local recurrence or distant metastatic disease for 1 and 2 years for the first and second patient accordingly. These cases contribute to a growing body of literature regarding ESC RCC including, to our knowledge, the first reported case of synchronous ESC RCC and clear cell RCC. Further research about this novel renal neoplasm is needed.<\/jats:p>","DOI":"10.1177\/1066896921993229","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T10:01:52Z","timestamp":1613988112000},"page":"747-751","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Two Cases of Sporadic Eosinophilic Solid and Cystic Renal Cell Carcinoma in Manitoba Population"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6455-5775","authenticated-orcid":false,"given":"Seyed Mohammad","family":"Mohaghegh Poor","sequence":"first","affiliation":[{"name":"Division of Urology, Department of Surgery, University of Manitoba College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivani","family":"Mathur","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, University of Manitoba College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Kassier","sequence":"additional","affiliation":[{"name":"Brandon Regional Health Centre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janetta","family":"Rossouw","sequence":"additional","affiliation":[{"name":"Brandon Regional Health Centre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Wightman","sequence":"additional","affiliation":[{"name":"Department of Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff","family":"Saranchuk","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, University of Manitoba College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3505-0262","authenticated-orcid":false,"given":"Ian W.","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,2,22]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000508"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000838"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/his.13457"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/his.13395"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2018.01.020"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001067"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001111"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2018.05.023"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.07.055"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2006.9937"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2018.10.027"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2018.06.007"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2018.06.040"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896921993229","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1066896921993229","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1066896921993229","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:22:10Z","timestamp":1777458130000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1066896921993229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,22]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1177\/1066896921993229"],"URL":"https:\/\/doi.org\/10.1177\/1066896921993229","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,22]]}}}