{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:26:08Z","timestamp":1777717568379,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T00:00:00Z","timestamp":1654732800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:p>Omenn syndrome, a rare form of combined immunodeficiency in infants, presenting with recurrent infections, erythroderma, lymphadenopathy, hepatosplenomegaly, eosinophilia, and increased serum IgE levels. It is a fatal condition unless treated by hematopoietic stem cell transplant. Hence, an early diagnosis and a prompt treatment can lead to better outcome in these unfortunate babies afflicted with Omenn syndrome. Here, we present an 8-week-old infant with typical features of Omenn syndrome, both clinically as well as on laboratory analysis, but surprising immunohistochemical findings on lymph node biopsy.<\/jats:p>","DOI":"10.1177\/10668969221098088","type":"journal-article","created":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T02:45:28Z","timestamp":1654829128000},"page":"64-68","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Concomitant Langerhans and Interdigitating Reticulum Cell Hyperplasia in a Reactive Lymph Node of an Infant with Omenn Syndrome: A Diagnostic Pitfall for Langerhans Cell Histiocytosis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0660-9939","authenticated-orcid":false,"given":"Md Ali","family":"Osama","sequence":"first","affiliation":[{"name":"Department of Pathology, Lady Hardinge Medical College, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nita","family":"Radhakrishnan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology-Oncology, Super Specialty Pediatric Hospital and Post Graduate Teaching Institute, Noida, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8294-8174","authenticated-orcid":false,"given":"Shashi","family":"Dhawan","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Sir Gangaram Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,6,9]]},"reference":[{"key":"bibr1-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.103319"},{"key":"bibr2-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196508192730806"},{"key":"bibr3-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199509000-00013"},{"key":"bibr4-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20020018"},{"key":"bibr5-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1002\/path.1344"},{"key":"bibr6-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-06-165266"},{"key":"bibr7-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2019.11.012"},{"key":"bibr8-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-07-099549"},{"key":"bibr9-10668969221098088","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-04-499442"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969221098088","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10668969221098088","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969221098088","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:22:34Z","timestamp":1777458154000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10668969221098088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,9]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1177\/10668969221098088"],"URL":"https:\/\/doi.org\/10.1177\/10668969221098088","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,9]]}}}