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In recent years, molecular markers have emerged that aid in the differentiation of benign and malignant mesothelial proliferations throughout the body. Here, we present two middle-aged men with well-differentiated papillary mesothelial tumors and a review of the literature. By now, more than a year after surgery, one patient showed no recurrence of disease after partial or complete orchiectomy without further treatment, for the second no information is available. In conclusion, well-differentiated papillary mesothelial tumors represent rare lesions in the tunica vaginalis testis, but one pathologists should know about to prevent unnecessary treatment and suffering of patients.<\/jats:p>","DOI":"10.1177\/10668969221129888","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T00:27:23Z","timestamp":1673310443000},"page":"1126-1131","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Well-differentiated Papillary Mesothelial Tumour of the Tunica Vaginalis Testis \u2013 A Rare Lesion, but one Pathologists Should Know About Two Patient Reports and a Review of the Literature"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5761-0713","authenticated-orcid":false,"given":"Johannes","family":"Kl\u00e4ger","sequence":"first","affiliation":[{"name":"Medical University Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicitas","family":"Oberndorfer","sequence":"additional","affiliation":[{"name":"Medical University Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristophe","family":"Brunel","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Central Institute, Sion, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Veser","sequence":"additional","affiliation":[{"name":"Medical University Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Comp\u00e9rat","sequence":"additional","affiliation":[{"name":"Medical University Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,1,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195701\/02)10:1<183::AID-CNCR2820100127>3.0.CO;2-1"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00431244"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.4132\/KoreanJPathol.2014.48.3.225"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000200"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2016.03.007"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/1066896916628279"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.4940"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjz040"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000281306"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00724916"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.45.11.1029"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.5858\/2000-124-0143-bpmott"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200110000-00012"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2005.06.021"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.113"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-6-78"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-018-0127-2"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2018.05.001"},{"key":"e_1_3_3_20_2","volume-title":"WHO Classification of Tumours Editorial Board. 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