{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T06:18:48Z","timestamp":1787811528272,"version":"build-2784847793"},"reference-count":19,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2023,2,19]],"date-time":"2023-02-19T00:00:00Z","timestamp":1676764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>\n                    Patent vitello-intestinal duct with adenoma is rare presentation. We report a case of a 1-month-old boy presenting with intermittent passage of stool and blood from the umbilicus since birth. On local examination polypoidal mass measuring 1\u00d71\u2005cm was seen protruding from umbilicus with faecal discharge. Ultrasound was performed which revealed a tubular hyperechoic structure, extending from umbilicus to part of small intestine measuring 30 \u00d730\u2005mm and clinical diagnosis of patent vitello-intestinal duct was given, exploratory laparotomy, excision with umbilicoplasty done, and send for histopathological examination. On histopathological examination, patent vitello-intestinal duct adenoma was rendered and next generation sequencing (NGS) was performed revealing somatic mutation of\n                    <jats:italic toggle=\"yes\">KRAS<\/jats:italic>\n                    (NM_033360.4; c.38G&gt;A; p.Gly12Asp). To our knowledge, this is the first report of the adenoma in patent vitello-intestinal duct with NGS analysis. This case emphasizes the importance of thorough microscopic examination of resected patent vitello-intestinal duct and mutational analysis of the early lesions\n                  <\/jats:p>","DOI":"10.1177\/10668969231152581","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T01:34:55Z","timestamp":1676856895000},"page":"1403-1408","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Next Generation Sequencing in Vitellointestinal Duct Adenoma: Existence of Adenoma-Carcinoma Sequence or too Early to Predict?"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0791-5417","authenticated-orcid":false,"given":"Pallavi","family":"Srivastava","sequence":"first","affiliation":[{"name":"Dr Ram Manohar Lohia Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sridhar","family":"Mishra","sequence":"additional","affiliation":[{"name":"Dr Ram Manohar Lohia Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saumya","family":"Shukla","sequence":"additional","affiliation":[{"name":"Dr Ram Manohar Lohia Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuzhat","family":"Husain","sequence":"additional","affiliation":[{"name":"Dr Ram Manohar Lohia Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,2,19]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"311","article-title":"Meckel\u2019s diverticulum","volume":"45","author":"Buchsbaum HJ","year":"1975","unstructured":"Buchsbaum HJ. 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