{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:26:58Z","timestamp":1787646418616,"version":"build-2736575974"},"reference-count":68,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T00:00:00Z","timestamp":1683158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["305077\/2021-0"],"award-info":[{"award-number":["305077\/2021-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:p>\n                    Cryptococcosis is a neglected fungal disease. The scarcity of studies on oral cryptococcosis is certainly due to rarity and\/or underreporting of the disease, especially in Brazil. We describe an example of orofacial cryptococcosis affecting a 57-year-old man after heart transplantation, who presented with multiple erythematous ulcers and erosions distributed in the chin, nasal cavity, labial mucosa, hard palate, and buccal vestibule. Computed tomography revealed opacities and micronodules in the lungs. Histopathological features of the oral and pulmonary lesions were compatible with\n                    <jats:italic toggle=\"yes\">Cryptococcus<\/jats:italic>\n                    spp. Amphotericin B and fluconazole were used for treatment during hospitalization and itraconazole for prolonged therapy after hospital discharge. The patient has been under follow up for 6 months without signs of disease. According to a review conducted in PubMed, Web of Science, Scopus, Embase, and LILACS for data analysis of oral cryptococcosis, 26 reports were described in the literature. Predilection for men was observed (85%), with a male:female ratio of 5.5:1. The mean age of the individuals was 49\u2009\u00b1\u200915.3 years. Oral cryptococcosis mostly presented as an ulcer (\n                    <jats:italic toggle=\"yes\">n\u2009<\/jats:italic>\n                    =\u200917). The palate and tongue were the most affected sites (\n                    <jats:italic toggle=\"yes\">n\u2009<\/jats:italic>\n                    =\u20099 for each). Amphotericin B was the primary therapy utilized in most patients. Seventeen (65%) individuals survived. Knowledge of the clinicodemographic aspects of oral cryptococcosis is important for clinicians in decision making and surveillance.\n                  <\/jats:p>","DOI":"10.1177\/10668969231169048","type":"journal-article","created":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T01:07:53Z","timestamp":1683248873000},"page":"165-181","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Orofacial Cryptococcosis: A Challenging Clinical Report and a Systematic Analysis of the Literature"],"prefix":"10.1177","volume":"32","author":[{"given":"Ana Carolina Velasco Pond\u00e9","family":"de Sena","sequence":"first","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6599-3950","authenticated-orcid":false,"given":"Jos\u00e9 Alcides Almeida","family":"de Arruda","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sic\u00edlia Rezende","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nickolas Mendes","family":"Pereira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa dos Santos","family":"Faria","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise Vieira","family":"Travassos","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"},{"name":"Universidade Federal de Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9623-7835","authenticated-orcid":false,"given":"Tarc\u00edlia Aparecida","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais"},{"name":"Universidade Federal de Minas Gerais"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,4]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2015.10.006"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13543"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2021.03.012"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa527"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30243-8"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/368091"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056269"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.13737"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1590\/s0034-89102009005000029"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004429"},{"key":"e_1_3_3_12_2","unstructured":"Neglected tropical diseases (NTDs). 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