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Here, we report the exceptional case of such a tumour in the setting of solid organ transplantation and with already metastatic disease at the time of diagnosis. The primary tumour occurred in the native kidney and only focally showed biphasic morphology whereas the metastasis, among others to the transplant kidney, showed nonspecific, albeit different morphology, but both had consistent\n                    <jats:italic toggle=\"yes\">TFEB<\/jats:italic>\n                    translocation. Treatment with the immune checkpoint inhibitor pembrolizumab together with the multi-kinase inhibitor lenvatinib achieved partial response 14 months after diagnosis.\n                  <\/jats:p>","DOI":"10.1177\/10668969231185070","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T02:19:49Z","timestamp":1688696389000},"page":"594-600","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Metastatic Translocated Renal Cell Carcinoma in a Kidney Transplant Patient - a Case Report and Review of the Literature"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5761-0713","authenticated-orcid":false,"given":"Johannes","family":"Kl\u00e4ger","sequence":"first","affiliation":[{"name":"Medical University of Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Schmidinger","sequence":"additional","affiliation":[{"name":"Medical University of Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Oszwald","sequence":"additional","affiliation":[{"name":"Medical University of Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Wasinger","sequence":"additional","affiliation":[{"name":"Medical University of Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harun","family":"Fajkovic","sequence":"additional","affiliation":[{"name":"Medical University of Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Comp\u00e9rat","sequence":"additional","affiliation":[{"name":"Medical University of Vienna"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,7,6]]},"reference":[{"key":"e_1_3_2_2_2","unstructured":"WHO Classification of Tumours Editorial Board. 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Metastatic renal cell carcinoma of the native kidney in a renal transplant recipient: revisiting the era of tyrosine kinase inhibitors \u2013 case report. Urol Case Rep. 2022;43:5-7.","journal-title":"Urol Case Rep"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002914"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2019.04.021"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08941.x"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1159\/000471600"},{"key":"e_1_3_2_19_2","volume-title":"Therapy-Related Secondary Cancers","author":"Rheingold SR","unstructured":"Rheingold SR, Neugut AI, Meadows AT. Therapy-Related Secondary Cancers. In: Kufe DW, Pollock RE, Weichselbaum RR, et al., eds. Holland-Frei Cancer Medicine. 6th edition. Hamilton, ON: BC Decker; 2003. 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