{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:32:51Z","timestamp":1787646771078,"version":"build-2736575974"},"reference-count":17,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T00:00:00Z","timestamp":1689552000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>\n                    Ischemic fasciitis is a pseudosarcomatous fibroblastic\/myofibroblastic proliferation that shares several overlapping morphological features with proliferative fasciitis and proliferative myositis. Prompted by a recent study that demonstrated FOS gene rearrangements in proliferative fasciitis and proliferative myositis, suggesting that these lesions likely represent examples of \u201ctransient neoplasia,\u201d we examined a cohort of ischemic fasciitis for similar events. Nine cases of ischemic fasciitis were retrieved from our institutional archives for diagnosis verification, immunostaining for FOSB, and fluorescence in situ hybridization using validated\n                    <jats:italic toggle=\"yes\">FOS<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">FOSB<\/jats:italic>\n                    break-apart probes. Additionally, RNAseq was performed on a subset of cases. In our cohort, eight out of nine cases of ischemic fasciitis were positive for FOSB IHC, but FISH studies were consistently negative for\n                    <jats:italic toggle=\"yes\">FOSB<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">FOS<\/jats:italic>\n                    gene rearrangements in all cases. Additionally, RNA sequencing did not detect any gene fusions. These findings suggest that the pathogenesis of ischemic fasciitis is distinct from that of proliferative fasciitis and proliferative myositis.\n                  <\/jats:p>","DOI":"10.1177\/10668969231188893","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T02:21:44Z","timestamp":1689646904000},"page":"726-730","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Lack of FOS\/FOSB Gene Rearrangements in Ischemic Fasciitis Indicates Distinct Pathogenesis from Proliferative Fasciitis and Proliferative Myositis"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2473-4474","authenticated-orcid":false,"given":"Megan L.","family":"Zilla","sequence":"first","affiliation":[{"name":"University of Pittsburgh Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5556-7376","authenticated-orcid":false,"given":"Rana","family":"Naous","sequence":"additional","affiliation":[{"name":"University of Pittsburgh Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4751-7678","authenticated-orcid":false,"given":"Ivy","family":"John","sequence":"additional","affiliation":[{"name":"University of Pittsburgh Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,7,17]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199207000-00009"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31816be8db"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-020-00725-2"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2018.0791"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2015.27.6.694"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2011.118"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-018-2350-0"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2013.03.005"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/his.13011"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000001147"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04530-z"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000000469"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000001695"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.4322"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13141"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000000795"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/his.14716"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969231188893","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10668969231188893","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969231188893","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:10:31Z","timestamp":1787645431000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10668969231188893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,17]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1177\/10668969231188893"],"URL":"https:\/\/doi.org\/10.1177\/10668969231188893","relation":{"has-review":[{"id-type":"doi","id":"10.1177\/10668969231188893\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10668969231188893\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10668969231188893\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10668969231188893\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10668969231188893\/v2\/decision1","asserted-by":"object"}]},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,17]]}}}