{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:30:40Z","timestamp":1787646640749,"version":"build-2736575974"},"reference-count":10,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T00:00:00Z","timestamp":1689552000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>While histological diagnosis of Paget disease of vulva is mostly straightforward, identifying and confirming invasion can be challenging. Often invasion is accompanied by epidermal hyperplasia, marked inflammatory response and desmoplastic reaction. Diagnosis of invasion in Paget disease portends a poor outcome. We report findings from a recurrent primary vulvar Paget disease where overall histomorphology of possible invasive disease is unusual and raises a possibility of displacement of Paget cells in the dermis. We compare histology of the index case with known invasive vulvar Paget disease cases retrieved from our pathology archives. Unique histomorphology in the index case suggests a possibility of previous excision related dermal displacement of Paget cells.<\/jats:p>","DOI":"10.1177\/10668969231188902","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T02:25:06Z","timestamp":1689647106000},"page":"507-510","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent Primary Paget Disease of Vulva with Paget-Like Epithelial Cells in Papillary Dermis: Displaced or Invasion?"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2935-4374","authenticated-orcid":false,"given":"Steffanie Charlyne","family":"Tamayo","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Women and Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1371-9095","authenticated-orcid":false,"given":"M. Ruhul","family":"Quddus","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Women and Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2506-5703","authenticated-orcid":false,"given":"Kamaljeet","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Women and Infants Hospital of Rhode Island and Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,7,17]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"445","volume-title":"Female genital tumors","author":"Gilks CB","year":"2020","unstructured":"Gilks CB, Yang B, Zannoni GF. Paget disease. In: WHO Classification of Tumours Editorial Board, eds. Female genital tumors. 5th ed. IARC; 2020:445-446.","edition":"5"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70143-2"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000001131"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2021.101581"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-020-05803-z"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2013.02.029"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.5858\/2005-129-1465-EDIBLA"},{"issue":"1","key":"e_1_3_2_9_2","article-title":"Bowel cancer screening-generated diagnostic conundrum of the century: pseudoinvasion in sigmoid colonic polyps","volume":"28","author":"Shepherd NA","year":"2015","unstructured":"Shepherd NA, Griggs RKL. Bowel cancer screening-generated diagnostic conundrum of the century: pseudoinvasion in sigmoid colonic polyps. Mod Pathol. 2015;28(Suppl 1):S88-S94.","journal-title":"Mod Pathol"},{"key":"e_1_3_2_10_2","first-page":"471","article-title":"Pseudoinvasive, nodular extramammary Paget\u2019s disease of the vulva","volume":"122","author":"Billings SD","year":"1998","unstructured":"Billings SD, Roth LM. Pseudoinvasive, nodular extramammary Paget\u2019s disease of the vulva. Arch Pathol Lab Med. 1998;122(5):471-474.","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199004000-00005"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969231188902","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10668969231188902","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969231188902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:09:30Z","timestamp":1787645370000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10668969231188902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,17]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1177\/10668969231188902"],"URL":"https:\/\/doi.org\/10.1177\/10668969231188902","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,17]]}}}